Italian Association of Hospital Cardiologists Position Paper ‘Gender discrepancy: time to implement gender-based clinical management’-Reference-Cited by-同舟云学术

Italian Association of Hospital Cardiologists Position Paper ‘Gender discrepancy: time to implement gender-based clinical management’

Published:2024-04 Issue:Supplement_2 Volume:26 Page:ii264-ii293
ISSN:1520-765X
Container-title:European Heart Journal Supplements
language:en
Short-container-title:

Author:

Lucà Fabiana¹^ORCID,Pavan Daniela²,Gulizia Michele Massimo³^ORCID,Manes Maria Teresa³,Abrignani Maurizio Giuseppe⁴,Benedetto Francesco Antonio¹,Bisceglia Irma⁵,Brigido Silvana⁶,Caldarola Pasquale⁷,Calvanese Raimondo⁸^ORCID,Canale Maria Laura⁹,Caretta Giorgio¹⁰,Ceravolo Roberto¹¹,Chieffo Alaide¹²,Chimenti Cristina¹³^ORCID,Cornara Stefano¹⁴,Cutolo Ada¹⁵,Di Fusco Stefania Angela¹⁶^ORCID,Di Matteo Irene¹⁷,Di Nora Concetta¹⁸,Fattirolli Francesco¹⁹,Favilli Silvia²⁰,Francese Giuseppina Maura³,Gelsomino Sandro²⁰,Geraci Giovanna²¹^ORCID,Giubilato Simona²²,Ingianni Nadia²³,Iorio Annamaria²⁴,Lanni Francesca²⁵,Montalto Andrea²⁶,Nardi Federico²⁷,Navazio Alessandro²⁸^ORCID,Nesti Martina²⁹,Parrini Iris³⁰,Pilleri Annarita³¹,Pozzi Andrea²⁴,Rao Carmelo Massimiliano¹,Riccio Carmine³²,Rossini Roberta³³^ORCID,Scicchitano Pietro³⁴^ORCID,Valente Serafina³⁵,Zuccalà Giuseppe³⁶,Gabrielli Domenico³⁷³⁸,Grimaldi Massimo³⁹^ORCID,Colivicchi Furio¹⁶,Oliva Fabrizio¹⁷

Affiliation:

1. Cardiology Department, Grande Ospedale Metropolitano GOM, Reggio Calabria, Via Melacriono , 1, 89129 Reggio, Calabria , Italy

2. Cardio-Cerebro-Rehabilitation Department, Azienda Sanitaria Friuli Occidentale , (AS FO) Via della Vecchia Ceramica, 1, Pordenone 33170 , Italy

3. Cardiology Unit, Cardiology Spoke Cetraro-Paola, San Franceco di paola Hospital , 87027 Paola, CS , Italy

4. Cardiology Unit, Cardiology “Paolo Borsellino” Hospital, Contrada Cardilla , 91025 Marsala, TP , Italy

5. Cardio-Thoraco-Vascular Department, San Camillo Forlanini Hospital , 00152 Roma , Italy

6. Cardiology Clinics, ‘F.’ Hospital Jaia’ , 70014 Conversano, BA , Italy

7. San Paolo Hospital , 70132 Bari , Italy

8. Ospedale del Mare di Napoli - ASL Napoli , 80147 Napoli , Italy

9. U.O.C. Cardiologia, Nuovo Ospedale Versilia , Lido di Camaiore , Italy

10. Cardiology Unit, Sant’Andrea Hospital , 19100 La Spezia, SP , Italy

11. Cardiology Division, Giovanni Paolo II Hospial , 88046 Lamezia Terme, CZ , Italy

12. Interventional Cardiology, IRCCS Ospedale San Raffaele , 20132 Milano , Italy

13. Department of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Policlinico Umberto I Hospital, Sapienza University of Rome , 00161 Roma , Italy

14. Levante Cardiology, San Paolo Hospital , Savona, 17100 Savona, SV , Italy

15. Cardiolog Unit, Ospedale dell’Angelo , 30172 Mestre , Italy

16. Cardiology Unit, San Filippo Neri Hospital , 00135 Roma , Italy

17. Cardiology Unit, Cariovascular Department , ‘A. De Gasperis’, ASST Grande Ospedale Metropolitano Niguarda, 20162 Milano , Italy

18. Cardiac Surgery Unit, Santa Maria della Misericordia Hospital , 33100 Udine, UD , Italy

19. Department of Experimental and Clinical Medicine , Florence University, 50121 Firenze , Italy

20. Pediatric and Transition Cardiology Unit, Meyer University Hospital , 50139 Florence , Italy

21. Cardiology Unit, Sant'Antonio Abate di Erice , 91016 Erice, Trapani , Italy

22. Cardiology Unit, Cannizzaro Hospital , Catania 95126 , Italy

23. Cardiologia, ASP Trapani , 91100 Trapani, TP , Italy

24. Cardiology Unity 1, Cardiology 1, Cardiovascular Department , Papa Giovanni XXIII Hospital, 24127 Bergamo , Italy

25. Cardiology Unity, San Giuseppe Moscati Hospital , 83100 Avellino , Italy

26. Cardiac Surgery Unit, San Camillo Forlanini Hospital , 00152 Roma , Italy

27. Dipartimento di Cardiologia, Ospedale Santo Spirito , Casale Monferrato , Italy

28. Cardiology Unity, San Camillo Forlanini Hospital , 00152 Roma , Italy

29. Cardiology Unity, San Donato Hospital , 52100 Arezzo , Italy

30. Cardiology Unity, Umberto I Di Torino Hospital , 10128 Torino , Italy

31. Federico Nardi, Cardiology Unit, Casale Monferrato Hospital , 15033 Casale Monferrato (AL) , Italy

32. Post-Acute Patient Follow-up Unit, Cardio-Vascular Department , AORN Sant'Anna and San Sebastiano, Caserta , Italy

33. Cardiology Department , 12100 Cuneo, CN , Italy

34. Ospedale Della Murgia “Fabio Perinei” , 70022 Altamura BA , Italy

35. Clinical-Surgical Cardiology, A.O.U. Siena, Santa Maria alle Scotte Hospital , 53100 Siena , Italy

36. Department of Geriatrics, Center for Aging Medicine , Catholic University of the Sacred Heart and IRCCS Fondazione Policlinico A. Gemelli, 00168 Rome , Italy

37. Dipartimento Cardio-Toraco-Vascolare, U.O.C. Cardiologia, Azienda Ospedaliera San Camillo Forlanini , Roma , Italy

38. Fondazione per il Tuo cuore—Heart Care Foundation , 50121 Firenze , Italy

39. Cardiology Division, Coronary Intensive Care Unit , Miulli Hospital, 70021 Acquaviva delle Fonti , Italy

Abstract

Abstract It has been well assessed that women have been widely under-represented in cardiovascular clinical trials. Moreover, a significant discrepancy in pharmacological and interventional strategies has been reported. Therefore, poor outcomes and more significant mortality have been shown in many diseases. Pharmacokinetic and pharmacodynamic differences in drug metabolism have also been described so that effectiveness could be different according to sex. However, awareness about the gender gap remains too scarce. Consequently, gender-specific guidelines are lacking, and the need for a sex-specific approach has become more evident in the last few years. This paper aims to evaluate different therapeutic approaches to managing the most common women’s diseases.

Funder

Centro Servizi ANMCO SrL—Società Benefit

Publisher

Oxford University Press (OUP)

Link

https://academic.oup.com/eurheartjsupp/article-pdf/26/Supplement_2/ii264/57682826/suae034.pdf

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