Cardio-oncology rehabilitation: are we ready?

Author:

Bisceglia Irma1,Venturini Elio2,Canale Maria Laura3,Ambrosetti Marco4,Riccio Carmine5,Giallauria Francesco6,Gallucci Giuseppina7,Abrignani Maurizio G8,Russo Giulia9,Lestuzzi Chiara10,Mistrulli Raffaella11,De Luca Giovanni12ORCID,Maria Turazza Fabio13,Mureddu Gianfrancesco14,Di Fusco Stefania Angela15ORCID,Lucà Fabiana16,De Luca Leonardo17,Camerini Andrea18,Halasz Geza19ORCID,Camilli Massimiliano2021ORCID,Quagliariello Vincenzo22,Maurea Nicola22,Fattirolli Francesco23,Gulizia Michele Massimo24ORCID,Gabrielli Domenico1925,Grimaldi Massimo26ORCID,Colivicchi Furio15,Oliva Fabrizio27

Affiliation:

1. Integrated Cardiology Services, Cardio-Thoracic-Vascular Department, Azienda Ospedaliera San Camillo Forlanini, C.ne Gianicolense , 87 00152 Rome , Italy

2. Department of Cardiac Rehabilitation, Cecina Civil Hospital, Via Montanara , 52, 57023 Cecina (LI) , Italy

3. Division of Cardiology, Azienda USL Toscana Nord-Ovest, Versilia Hospital, Via Aurelia , 335, 55041 Lido di Camaiore (LU) , Italy

4. Unità Operativa Complessa di Riabilitazione Cardiologica, ASST Crema Ospedale Santa Marta , Rivolta D'Adda, 26027 Cremona , Italy

5. Dipartimento Cardio-Vascolare, AORN Sant'Anna e San Sebastiano , Caserta , Italy

6. Department of Translational Medical Sciences, University of Naples Federico II , Naples , Italy

7. Cardio-oncologist , Melfi, 85025 Potenza , Italy

8. U.O di Cardiologia, P.O. ‘P. Borsellino’ , Marsala, ASP Trapani , Italy

9. SC Patologie Cardiovascolari, Ospedale Maggiore, Via Slataper , 9, 34125 Trieste , Italy

10. Centro Medico Esperia , Porcia, PN , Italy

11. Cardiology Unit, Department of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, Sapienza University of Rome, Sant'Andrea Hospital , Rome , Italy

12. Health Activities and Epidemiologic Observatory Division, Health Department, Sicily Region , Piazza O. Ziino, 24, 90145 Palermo , Italy

13. Director of Cardiology, IRCCS Foundation, National Cancer Institute, via G Venezian , 1, 20133 Milano , Italy

14. Cardiology Division, S. Giovanni Hospital , Via dell'Amba Aradam, 8, 00184 Rome , Italy

15. Clinical and Rehabilitation Cardiology Unit, San Filippo Neri Hospital, Via Martinotti , 20, 00135 Roma , Italy

16. Cardiology Department, Grande Ospedale Metropolitano, GOM, AO Bianchi Melacrino Morelli , 89129 Reggio di Calabria , Italy

17. SC Cardiologia, Fondazione IRCCS San Matteo, Viale Camillo Golgi , 19, 27100 Pavia , Italy

18. Department of Medical Oncology, Azienda USL Toscana Nord-Ovest, Versilia Hospital,Via Aurelia , 335, 55041 Lido di Camaiore (LU) , Italy

19. Dipartimento Cardio-Toraco-Vascolare, U.O.C. Cardiologia, Azienda Ospedaliera San Camillo-Forlanini, C.ne Gianicolense , 87, 00152 Rome , Italy

20. Department of Cardiovascular Medicine, Fondazione Policlinico Universitario A. Gemelli, IRCCS, L.go A. Gemelli , 1, 00168 Rome , Italy

21. Department of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart, L.go Francesco Vito , 00168 Rome , Italy

22. Division of Cardiology, National Cancer Institute, Sen. Pascale Foundation , via Mariano Semmola, 80131 Napoli , Italy

23. Azienda Ospedaliero - Universitaria Careggi, Largo Brambilla , 3, 50134 Firenze , Italy

24. Cardiothoracic Department, Garibaldi Nesima Hospital , 95122 Catania , Italy

25. Fondazione per il Tuo cuore—Heart Care Foundation , Firenze, Via A. La Marmora, 36, 50121 Firenze , Italy

26. Regional General Hospital F. Miulli , Strada Prov. 127 Acquaviva – Santeramo Km, 4, 100.70021 Acquaviva delle Fonti (BARI) , Italy

27. Cardiologia 1-Emodinamica Dipartimento Cardiotoracovascolare ‘A. De Gasperis’, ASST Grande Ospedale Metropolitano Niguarda , 20162 Milan , Italy

Abstract

Abstract Cardio-oncology rehabilitation (CORE) is not only an essential component of cancer rehabilitation but also a pillar of preventive cardio-oncology. Cardio-oncology rehabilitation is a comprehensive model based on a multitargeted approach and its efficacy has been widely documented; when compared with an ‘exercise only’ programme, comprehensive CORE demonstrates a better outcome. It involves nutritional counselling, psychological support, and cardiovascular (CV) risk assessment, and it is directed to a very demanding population with a heavy burden of CV diseases driven by physical inactivity, cancer therapy-induced metabolic derangements, and cancer therapy-related CV toxicities. Despite its usefulness, CORE is still underused in cancer patients and we are still at the dawning of remote models of rehabilitation (tele-rehabilitation). Not all CORE is created equally: a careful screening procedure to identify patients who will benefit the most from CORE and a multidisciplinary customized approach are mandatory to achieve a better outcome for cancer survivors throughout their cancer journey. The aim of this paper is to provide an updated review of CORE not only for cardiologists dealing with this peculiar population of patients but also for oncologists, primary care providers, patients, and caregivers. This multidisciplinary team should help cancer patients to maintain a healthy and active life before, during, and after cancer treatment, in order to improve quality of life and to fight health inequities.

Funder

Centro Servizi ANMCO SrL — Società Benefit

Publisher

Oxford University Press (OUP)

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