SERAPHIN haemodynamic substudy: the effect of the dual endothelin receptor antagonist macitentan on haemodynamic parameters and NT-proBNP levels and their association with disease progression in patients with pulmonary arterial hypertension

Author:

Galiè Nazzareno1,Jansa Pavel2,Pulido Tomás3,Channick Richard N.4,Delcroix Marion5,Ghofrani Hossein-Ardeschir6,Le Brun Franck-Olivier7,Mehta Sanjay8,Perchenet Loïc7,Rubin Lewis J.9,Sastry B.K.S.10,Simonneau Gérald11,Sitbon Olivier11,Souza Rogério12,Torbicki Adam13

Affiliation:

1. Department of Experimental, Diagnostic and Specialty Medicine-DIMES, via Massarenti 9, Bologna 40138, Italy

2. Clinical Department of Cardiology and Angiology, 1st Faculty of Medicine, 2nd Medical Department, Charles University, Prague, Czech Republic

3. Cardiopulmonary Department, Ignacio Chávez, National Heart Institute, Mexico City, Mexico

4. Pulmonary and Critical Care, Massachusetts General Hospital, Boston, MA, USA

5. Department of Pneumology, Gasthuisberg University Hospital, Leuven, Belgium

6. University of Giessen and Marburg Lung Center (UGMLC), Giessen, Germany, Member of the German Center of Lung Research (DZL), and Department of Medicine, Imperial College London, London, UK

7. Actelion Pharmaceuticals Ltd, Allschwil, Switzerland

8. Division of Respirology, Department of Medicine, London Health Sciences Centre, Victoria Hospital, Western University, London, ON, Canada

9. Division of Pulmonary and Critical Care Medicine, University of California, San Diego Medical School, San Diego, CA, USA

10. Department of Cardiology, CARE Hospitals, Hyderabad, India

11. Assistance Publique-Hôpitaux de Paris, Service de Pneumologie, Hôpital Bicêtre, Université Paris-Sud, Laboratoire d'Excellence en Recherche sur le Médicament et Innovation Thérapeutique, and INSERM U-999, Le Kremlin-Bicêtre, France

12. Pulmonary Department, Heart Institute, University of São Paulo Medical School, São Paulo, Brazil

13. Department of Pulmonary Circulation and Thromboembolic Diseases, Medical Center for Postgraduate Education, ECZ-Otwock, Poland

Publisher

Oxford University Press (OUP)

Subject

Cardiology and Cardiovascular Medicine

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