Definition of hidden drug cardiotoxicity: paradigm change in cardiac safety testing and its clinical implications-Reference-Cited by-同舟云学术

Definition of hidden drug cardiotoxicity: paradigm change in cardiac safety testing and its clinical implications

Published:2018-07-02 Issue:22 Volume:40 Page:1771-1777
ISSN:0195-668X
Container-title:European Heart Journal
language:en
Short-container-title:

Author:

Ferdinandy Péter¹²,Baczkó István³,Bencsik Péter²,Giricz Zoltán¹²,Görbe Anikó¹²,Pacher Pál⁴,Varga Zoltán V¹⁴,Varró András³,Schulz Rainer⁵

Affiliation:

1. Department of Pharmacology and Pharmacotherapy, Semmelweis University, Nagyvárad tér 4, Budapest, Hungary

2. Pharmahungary Group, Hajnoczy u. 6, Szeged, Hungary

3. Department of Pharmacology and Pharmacotherapy, University of Szeged, Dóm tér 12, Szeged, Hungary

4. Laboratory of Cardiovascular Physiology and Tissue Injury, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Fishers Lane, Bethesda, MD, USA

5. Institute of Physiology, Justus-Liebig University of Giessen, Aulweg 129, Giessen, Germany

Funder

European Co-operation in Science and Technology

Hungarian National Research, Development, and Innovation Office

German Research Foundation

Higher Education Institutional Excellence Programme of the Ministry of Human Capacities in Hungary

Therapeutic Development

Semmelweis University

Premium Postdoctoral Fellowship Program of the Hungarian Academy of Sciences

Publisher

Oxford University Press (OUP)

Subject

Cardiology and Cardiovascular Medicine

Link

http://academic.oup.com/eurheartj/article-pdf/40/22/1771/28772176/ehy365.pdf

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4. Effective analgesic doses of tramadol or tapentadol induce brain, lung and heart toxicity in Wistar rats;Faria;Toxicology,2017

5. . Drug-induced torsades de pointes and implications for drug development;Fenichel;J Cardiovasc Electrophysiol,2004

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