Use of cardiac imaging in chronic coronary syndromes: the EURECA Imaging registry-Reference-Cited by-同舟云学术

Use of cardiac imaging in chronic coronary syndromes: the EURECA Imaging registry

Published:2022-12-01 Issue:2 Volume:44 Page:142-158
ISSN:0195-668X
Container-title:European Heart Journal
language:en
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Neglia Danilo¹²^ORCID,Liga Riccardo³⁴^ORCID,Gimelli Alessia¹^ORCID,Podlesnikar Tomaž⁵⁶^ORCID,Cvijić Marta⁵⁷,Pontone Gianluca⁸^ORCID,Miglioranza Marcelo Haertel⁹¹⁰¹¹^ORCID,Guaricci Andrea Igoren¹²^ORCID,Seitun Sara¹³^ORCID,Clemente Alberto¹^ORCID,Sumin Alexey¹⁴^ORCID,Vitola João¹⁵^ORCID,Saraste Antti¹⁶^ORCID,Paunonen Christian¹⁶,Sia Ching-Hui¹⁷^ORCID,Paleev Filipp¹⁸^ORCID,Sade Leyla Elif¹⁹^ORCID,Zamorano Jose Luis²⁰^ORCID,Maroz-Vadalazhskaya Natallia²¹^ORCID,Anagnostopoulos Constantinos²²^ORCID,Macedo Filipe²³^ORCID,Knuuti Juhani²⁴^ORCID,Edvardsen Thor²⁵²⁶^ORCID,Cosyns Bernard²⁷²⁸^ORCID,Petersen Steffen E²⁹³⁰^ORCID,Magne Julien³¹³²³³^ORCID,Laroche Cecile³⁴,Berlè Clara³⁴,Popescu Bogdan A³⁵^ORCID,Delgado Victoria³⁶³⁷^ORCID,Gyongyosi M,Graf S,Spannbauer A,Han E,Muller C,Radziyeuskaya A,Rakhatsevich K,Kauhanka M,Badziukova L,Kolva E,Zhuk O,Hryb S,Maroz-Vadalazhskaya N,Zakharevich A,Cosyns B,Azzano A,Vandeloo B,Roosens B,Weytjens C,Plein D,Schoors D,Lemoine I,Argacha J-F,Van Den Bussche K,Soens L,Lochy S,Droogmans S,Vitola J,Morita M,Cerci R,De Paula E,Miglioranza M Haertel,Cella P A M,Vieira J L d C,Birk L,Guimarães R B,Terra D H,Saad A,Ali M,Airaksinen J,Saraste A,Paunonen C,Lahtonen K,Vasankari T,Rochette G Barone,Hildt J,Charlon C,Hyafil F,Scalbert F,Chequer R,Rouzet F,Lairez O,Blanc A,Dang D,Cariou E,Sanchis K,Larroche J,Lemasle M,Pascal P,Revel-Mouroz P,Cazalbou S,Sayir S,Blanchard V,Houard V,Lavie-Badie Y,Ikonomidis I,Katogiannis K,Marsonis A,Manginas A,Boutsikou M,Styliadis I,Moralidis E,Sotiriou S,Sachpekidis V,Maurovich-Horvat P,Boussoussou M,Suhai F,Kolossváry M,Jermendy A,Borzsák S,Simon J,Szilveszter B,Csore J,Vattay B,Vecsey-Nagy M,Sepp R,Thury A,Séllei Á,Farkas A,Farkas A,Polestyuk B,Nagy F Tamás,Csadi R,Favale S,Guaricci A I,Scardapane A,Napoli F V,Lepera M E,Ruggieri R,Marangelli V,Achille T,Marchionni N,Carrabba N,Migliorini A,Valenti R,Ceschia N,Ciatti F,Castellan L,Seitun S,Bauckneht M,De Lorenzi C,Porto I,Ameri P,Sambuceti G,Pescetelli F,Casolo G,Del Meglio J,Poddighe R,Rigo F,Spadotto V,Moreo A,Milazzo A,De Chiara B,Musca F,Casadei F,Quattrocchi G,Santambrogio G M,Belli O E,Pedrotti P,Sormani P,Merlini P A,Spano F,Sun J,Palazzini M,Pontone G,Guglielmo M,Scafuri S,Condorelli G,Rossi A,Fazzari F,Parati G,Giuliano A,Tanese N,Guida V,Branzi G,Perrone-Filardi P,Paolillo S,Gargiulo P,Esposito I,Dell Aversana S,Marsico F,Gaibazzi N,Suma S,De Caterina R,Lattanzi F,Morrone D,Liga R,Conti U,Chiappino D,Emdin M,Berti S,Gimelli A,Decaterina A,Clemente A,Giannoni A,Barison A,Neglia D,Pasanisi E,Coceani M,Spini V,Lanza G A,Melita V,Ravenna E,De Vita A,Mancone M,Infusino F,Montefusco G,Tocci M,Salvi N,Pino P G,Genuardi L,Manzara C,Celli P,Sanna G D,Parodi G,Dossi F,Marini A,Cameli M,Mandoli G E,Contorni F,Faganello G,Furlotti S,Porcari A,Pagura L,Zaccari M,Nuzzi V,Vaskelyte J J,Zvirblyte R,Sakaviciute E,Virsinskaite R,Celutkiene J,Balkeviciene L,Dvinelis E,Scholte A,Van Hout M,Edvardsen T,Tangen J,Melberg K,Ribe M,Golba K,Goscinska-Bis K,Szyszka A,Dankowski R,Plonska-Gosciniak E,Stepien M,Piatek P,Bedkowski K,Teixeira R,Saleiro C,Lopes J,Sousa J,Pais A,Fernandes M,Lourenco A,Cardoso F,Ferreira F,Portugues J,Almeida A,Nunes-Ferreira A,Veiga A,David C,Caldeira D,Cantinho G,Cunha N,Rodrigues T,Macedo F,Paiva M,Sousa C,Resende X,Vasconcelos M,Diogo P,de Carvalho M Martins,Mendes L,Reis C,Melo I,Patinha J,Santos J,Castro M,Amado P,Rodrigues R,Balão S,Lima S,Madeira V,Benedek T,Mester A,Opincariu D,Rodean I,Benedek I S,Ratiu M,Hodas R,Licu R,Rachkova S,Krotova M,Belova O,Sumin A,Kokov A,Gorbunova E,Polikutina O,Korok E,Korotkevich A,Shcheglova A,Lebedeva O,Basinkevich A,Ageev F,Bubnov D,Blankova Z,Subotnikov M,Efindeeva S,Gavrushina S,Polanskaya T,Kozlova E,Nuraliev E,Kolmakova T,Shamrina N,Smirnova L,Orlova E,Sonina A,Loginova A,Zhigunova L,Smirnova M,Osokina A,Korobova E,Tsagareishvili E,Svirida O,Dergousov P,Borisov A,Kuznetsova M,Silvestrova G,Kotova L,Gavrilova K,Fofanova T,Guchaev R,Vitsenya M,Merzlikina Y,Zhukova N,Kaziev R,Gazizova V,Filippov E,Moseichuk K,Zavadovsky K,Boshchenko A,Kopeva K,Mochula A,Maltseva A,Grakova E,Dikic A Djordjevic,Beleslin B,Boskovic N,Petrovic M,Giga V,Dedic S,Dodic S,Dabovic D,Ilic A,Bjelobrk M,Cankovic M,Jarakovic M,Tomas I,Bjelic S,Tadic S,Miljkovic T,Popov T,Sia C-H,Wong R Ching-Chiew,Poh K-K,Kong W K,Podlesnikar T,Berlot B,Stalc M,Maiga H,Salobir B Guzic,Ambrozic J,Jovanovic M,Mrak M,Skafar M,Toplisek J,Ovsenik A,Bervar M,Dolenc M,Pavsic N,Segulin B,Rauber M,Cvijic M,Vitez L,Jug B,Berden P,Zbacnik R,Bouzas-Mosquera A,Peteiro J,Aguadé-Bruix S,Coll C Espinet,Pizzi N,Rodríguez D Alonso,Centellas A Martin,Terol B,Ponz I,Lopez T,Monzonis M-A Martinez,Fernandez B Diaz,Antonio C Cacho,Fortuni A Torrelles,Dominguez M Perez,Campos A Garcia,Pais J Lopez,Engblom H,Sakaria A,Jarnhall P,Buechel R R,Sade L E,Bal U Abbas,Karacaglar E,Abbas U,Barutcu A,Arslan M,Ural D,Aslan G,Yurtseven E,Uygur B,Yildirim C,Corekcioglu B,Ozpelit E,Kakar H,Erkol A,Ozen D Kaptan,Turan B,Acar B,Yilmaz S,

Affiliation:

1. Cardiovascular and Imaging Departments, Fondazione Toscana G. Monasterio , Via Giuseppe Moruzzi, 1, 56124 Pisa , Italy

2. Sant’Anna School of Advanced Studies , Piazza Martiri della Libertà, 33, 56127 Pisa , Italy

3. Dipartimento di Patologia Chirurgica, Medica, Molecolare e dell’ Area Critica, University of Pisa , Via Savi 10, 56126 Pisa , Italy

4. Dipartimento Cardiotoraco Vascolare, Azienda Ospedaliero-Universitaria Pisana , Via Paradisa, 2, 56124 Pisa , Italy

5. Department of Cardiology, University Medical Centre Ljubljana , Zaloška cesta 2, 1000 Ljubljana , Slovenia

6. Department of Cardiac Surgery, University Medical Centre Maribor , Ljubljanska ulica 5, 2000 Maribor , Slovenia

7. Faculty of Medicine, University of Ljubljana , Vrazov trg 2, 1000 Ljubljana , Slovenia

8. Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS , Via Carlo Parea, 4, 20138 Milano , Italy

9. EcoHaertel—Mae de Deus Hospital , R. José de Alencar, 286 - Menino Deus, Porto Alegre - RS, 90880-481 , Brazil

10. Federal University of Health Sciences of Porto Alegre (UFCSPA) , R. Sarmento Leite, 245 - Centro Histórico, Porto Alegre - RS, 90050-17 , Brazil

11. Institute of Cardiology—University Foundation of Cardiology , R. Sarmento Leite, 245 - Centro Histórico, Porto Alegre - RS, 90050-170 , Brazil

12. Department of Emergency and Organ Transplantation, Institute of Cardiovascular Disease, University Hospital ‘Policlinico’ of Bari , Piazza Giulio Cesare, 11, 70124 Bari , Italy

13. Department of Radiology, IRCCS Policlinico San Martino Hospital , Largo Rosanna Benzi, 10, 16132 Genova , Italy

14. Federal State Budgetary Scientific Institution “Research Institute for Complex Issues of Cardiovascular Diseases” , Sosnoviy Blvd., 6, 650002 Kemerovo , Russian Federation

15. Quanta Diagnostico por Imagem , R. Alm. Tamandaré, 1000 - Alto da XV, Curitiba - PR, 80045-170 , Brazil

16. Heart Centre, Turku University Hospital and University of Turku , Kiinamyllynkatu 4-8, 20521 Turku , Finland

17. National University Heart Centre Singapore , 5 Lower Kent Ridge Rd, 119074 Singapore , Singapore

18. National Medical Research Center of Cardiology , 3-Ya Cherepkovskaya Ulitsa, 15A, 121552 Moscow , Russian Federation

19. Department of Cardiology, University of Baskent , Yukarı Bahçelievler, Mareşal Fevzi Çakmak Cd. No: 45, 06490 Çankaya/Ankara , Turkey

20. Department of Cardiology, Ramon Y Cajal University Hospital , M-607, 9, 100, 28034 Madrid , Spain

21. Department of General Practice, Division of Postgraduate Education, Belarusian State Medical University , Dzerzhinski Ave 83, 220083 Minsk , Belarus

22. PET-CT Department & Preclinical Imaging Unit, Centre for Experimental Surgery, Clinical and Translational Research, Biomedical Research Foundation Academy of Athens , 4 Soranou Ephessiou Street, 115 27 Athens , Greece

23. Cardiology Department, S João University Hospital , Alameda Prof. Hernâni Monteiro, 4200-319 Porto , Portugal

24. Turku PET Centre, Turku University Hospital and University of Turku , c/o Turku University Hospital, Kiinamyllynkatu 4-8, 20520 Turku , Finland

25. Department of Cardiology, Oslo University Hospital, Rikshospitalet , Kirkeveien 166, 0450 Oslo , Norway

26. Institute of Clinical Medicine, University of Oslo , Klaus Torgårds vei 3, 0372 Oslo , Norway

27. Centrum voor Hart en Vaatziekten, Universtair Ziekenhuis Brussel , Av. du Laerbeek 101, 1090 Bruxelles , Belgium

28. In Vivo Molecular and Cellular Imaging Center, Universitair Ziekenhuis Brussel , Laarbeeklaan 101, 1090 Jette , Belgium

29. Barts Heart Center, St. Bartholomew’s Hospital , West Smithfield, W Smithfield, London EC1A 7BE , UK

30. NIHR Barts Biomedical Research Centre, William Harvey Research Institute, Queen Mary University of London , Charterhouse Square, London EC1M 6BQ , UK

31. Inserm Unit 1094 and IRD, Faculty of Medicine, Limoges University , 2 rue du Dr Marcland, 87025 Limoges , France

32. Centre of Epidemiology, Biostatistic and Methodology of Research, University Hospital , Limoges, 2 Av. Martin Luther King, 87000 Limoges , France

33. Department of Cardiology, Dupuytren-2 University Hospital , 16 rue Bernard Descottes, 87042 Limoges , France

34. The European Society of Cardiology, The European Heart House , Sophia Antipolis Cedex, 2035 Rte des Colles, 06410 Biot , France

35. Department of Cardiology, University of Medicine and Pharmacy ‘Carol Davila’, Euroecolab, Emergency Institute for Cardiovascular Diseases ‘Prof. Dr. C. C. Iliescu’ , Bulevardul Eroii Sanitari 8, 050474 București , Romania

36. Department of Cardiology, Leiden University Medical Centre , Albinusdreef 2, 2333 ZA Leiden , The Netherlands

37. Heart Institute, Hospital University Germans Trias i Pujol , Carretera de Canyet, s/n, 08916, Badalona, Barcelona , Spain

Abstract

Abstract Background The prospective, multicentre EURECA registry assessed the use of imaging and adoption of the European Society of Cardiology (ESC) Guidelines (GL) in patients with chronic coronary syndromes (CCS). Methods Between May 2019 and March 2020, 5156 patients were recruited in 73 centres from 24 ESC member countries. The adoption of GL recommendations was evaluated according to clinical presentation and pre-test probability (PTP) of obstructive coronary artery disease (CAD). Results The mean age of the population was 64 ± 11 years, 60% of patients were males, 42% had PTP >15%, 27% had previous CAD, and ejection fraction was <50% in 5%. Exercise ECG was performed in 32% of patients, stress imaging as the first choice in 40%, and computed tomography coronary angiography (CTCA) in 22%. Invasive coronary angiography (ICA) was the first or downstream test in 17% and 11%, respectively. Obstructive CAD was documented in 24% of patients, inducible ischaemia in 19%, and 13% of patients underwent revascularization. In 44% of patients, the overall diagnostic process did not adopt the GL. In these patients, referral to stress imaging (21% vs. 58%; P < 0.001) or CTCA (17% vs. 30%; P < 0.001) was less frequent, while exercise ECG (43% vs. 22%; P < 0.001) and ICA (48% vs. 15%; P < 0.001) were more frequently performed. The adoption of GL was associated with fewer ICA, higher proportion of diagnosis of obstructive CAD (60% vs. 39%, P < 0.001) and revascularization (54% vs. 37%, P < 0.001), higher quality of life, fewer additional testing, and longer times to late revascularization. Conclusions In patients with CCS, current clinical practice does not adopt GL recommendations on the use of diagnostic tests in a significant proportion of patients. When the diagnostic approach adopts GL recommendations, invasive procedures are less frequently used and the diagnostic yield and therapeutic utility are superior.

Funder

Abbott Vascular Int

Amgen Cardiovascular

AstraZeneca

Bayer AG

Boehringer-Ingelheim

Boston Scientific

The Bristol Myers Squibb and Pfizer Alliance

Daiichi Sankyo Europe GmbH

The Alliance Daiichi Sankyo Europe GmbH and Eli Lilly and Company

Edwards

Gedeon Richter Plc