1. Department of Medicine, Hualien Armed Forces General Hospital , No. 100, Jinfeng St., Hualien City 970 , Taiwan
2. Department of Medicine, Tri-Service General Hospital, National Defense Medical Center , Taipei 114 , Taiwan
3. Department of Stomatology of Periodontology, Mackay Memorial Hospital , Taipei 104 , Taiwan
4. John Ochsner Heart and Vascular Institute, Ochsner Clinical School, The University of Queensland School of Medicine , New Orleans, LA 70121 , USA