Computational modelling in health and disease: highlights of the 6th annual SysMod meeting

Author:

Niarakis Anna12ORCID,Thakar Juilee34ORCID,Barberis Matteo567ORCID,Rodríguez Martínez María8ORCID,Helikar Tomáš9ORCID,Birtwistle Marc1011ORCID,Chaouiya Claudine12ORCID,Calzone Laurence131415ORCID,Dräger Andreas16171819ORCID

Affiliation:

1. GenHotel, Department of Biology, Univ Évry, University of Paris-Saclay, Genopole , 91025 Évry, France

2. Lifeware Group, Inria Saclay-île de France , Palaiseau 91120, France

3. Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry , Rochester, NY, USA

4. Department of Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry , Rochester, NY, USA

5. Systems Biology, School of Biosciences and Medicine, Faculty of Health and Medical Sciences, University of Surrey , GU2 7XH Guildford, Surrey, UK

6. Centre for Mathematical and Computational Biology, CMCB, University of Surrey , GU2 7XH Guildford, Surrey, UK

7. Synthetic Systems Biology and Nuclear Organization, Swammerdam Institute for Life Sciences University of Amsterdam , 1098 XH Amsterdam, The Netherlands

8. IBM Research Europe , Rueschlikon 8803, Switzerland

9. Department of Biochemistry, University of Nebraska-Lincoln , Lincoln, NE68588-0664, USA

10. Department of Chemical and Biomolecular Engineering, Clemson University , Clemson, SC 29634, USA

11. Department of Bioengineering, Clemson University , Clemson, SC 29634, USA

12. Aix-Marseille Univ, CNRS, I2M , Marseille 13009, France

13. Institut Curie, PSL Research University , Paris, France

14. INSERM, U900 , Paris, France

15. MINES ParisTech , Paris, France

16. Computational Systems Biology of Infections and Antimicrobial-Resistant Pathogens, Institute for Bioinformatics and Medical Informatics (IBMI), Eberhard Karl University of Tübingen , 72076 Tübingen, Germany

17. Department of Computer Science, Eberhard Karl University of Tübingen , 72076 Tübingen, Germany

18. German Center for Infection Research (DZIF), Partner Site Tübingen , Tübingen 72076, Germany

19. Cluster of Excellence ‘Controlling Microbes to Fight Infections,’ Eberhard Karl University of Tübingen , Tübingen 72076, Germany

Abstract

Abstract Summary The Community of Special Interest (COSI) in Computational Modelling of Biological Systems (SysMod) brings together interdisciplinary scientists interested in combining data-driven computational modelling, multi-scale mechanistic frameworks, large-scale -omics data and bioinformatics. SysMod’s main activity is an annual meeting at the Intelligent Systems for Molecular Biology (ISMB) conference, a meeting for computer scientists, biologists, mathematicians, engineers and computational and systems biologists. The 2021 SysMod meeting was conducted virtually due to the ongoing COVID-19 pandemic (coronavirus disease 2019). During the 2-day meeting, the development of computational tools, approaches and predictive models was discussed, along with their application to biological systems, emphasizing disease mechanisms. This report summarizes the meeting. Availability and implementation All resources and further information are freely accessible at https://sysmod.info.

Funder

Symbiont

Systems Biology Grant of the University of Surrey

NIH

Horizon 2020

NIH/NIGMS

DFG, German Research Foundation

Cluster of Excellence EXC 2124 Controlling Microbes to Fight Infections

Publisher

Oxford University Press (OUP)

Subject

Computational Mathematics,Computational Theory and Mathematics,Computer Science Applications,Molecular Biology,Biochemistry,Statistics and Probability

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