1. West China Biomedical Big Data Center, West China Hospital, Sichuan University, Chengdu 610041, China
2. Med-X Center for Informatics, Sichuan University, Chengdu 610041, China
3. Center for Computational Systems Medicine, School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA
4. College of Electronic and Information Engineering, Tongji University, Shanghai, Shanghai 201804, China
5. School of Life Sciences and Technology, Xidian University, Xi’an 710126, China
6. McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA
7. School of Dentistry, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA