Kidney function changes in acute heart failure: a practical approach to interpretation and management

Author:

Kenneally Laura Fuertes12,Lorenzo Miguel3ORCID,Romero-González Gregorio45ORCID,Cobo Marta67ORCID,Núñez Gonzalo3,Górriz Jose Luis8ORCID,Barrios Ana Garcia12,Fudim Marat910,de la Espriella Rafael3,Núñez Julio36ORCID

Affiliation:

1. Cardiology Department, General Hospital of Alicante, Dr Balmis . Alicante , Spain

2. Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIAL) . Alicante , Spain

3. Cardiology Department, Hospital Clínico Universitario de Valencia, Universitat de Valencia, INCLIVA , Valencia , Spain

4. Nephrology Department, University Hospital Germans Trias I Pujol , Badalona , Spain , , Vicenza , Italy

5. International Renal Research Institute of Vicenza (IRRIV) , Badalona , Spain , , Vicenza , Italy

6. CIBER Cardiovascular

7. Cardiology Department, Hospital Universitario Puerta de Hierro Majadahonda (IDIPHISA) , Madrid , Spain

8. Nephrology Department, Hospital Clínico Universitario de Valencia, Universitat de Valencia , Valencia , Spain

9. Cardiology Department, Duke University Medical Center . Durham, NC , USA

10. Duke Clinical Research Institute , Durham, NC , USA

Abstract

ABSTRACT Worsening kidney function (WKF) is common in patients with acute heart failure (AHF) syndromes. Although WKF has traditionally been associated with worse outcomes on a population level, serum creatinine concentrations vary greatly during episodes of worsening heart failure, with substantial individual heterogeneity in terms of their clinical meaning. Consequently, interpreting such changes within the appropriate clinical context is essential to unravel the pathophysiology of kidney function changes and appropriately interpret their clinical meaning. This article aims to provide a critical overview of WKF in AHF, aiming to provide physicians with some tips and tricks to appropriately interpret kidney function changes in the context of AHF.

Funder

FIS

CIBER

Publisher

Oxford University Press (OUP)

Subject

Transplantation,Nephrology

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