Detection of Epidemic Scarlet Fever Group A Streptococcus in Australia

Author:

Walker Mark J1,Brouwer Stephan1,Forde Brian M1,Worthing Kate A2,McIntyre Liam2,Sundac Lana3,Maloney Sam3,Roberts Leah W1,Barnett Timothy C1,Richter Johanna1,Cork Amanda J1,Irwin Adam D45,You Yuanhai6,Zhang Jianzhong6,Dougan Gordon7,Yuen Kwok Y8910,Nizet Victor11,Beatson Scott A1,Grimwood Keith1213,Davies Mark R2

Affiliation:

1. Australian Infectious Diseases Research Centre, University of Queensland, Brisbane

2. Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Victoria, Australia

3. Pathology Queensland, Gold Coast Laboratory, Brisbane, Australia

4. University of Queensland Centre for Clinical Research, Brisbane, Australia

5. Queensland Children’s Hospital, Brisbane, Australia

6. State Key Laboratory of Infectious Disease Prevention and Control, Collaborative Innovation, Center for Diagnosis and Treatment of Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing

7. Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom

8. Department of Microbiology, University of Hong Kong, Hong Kong Special Administrative Region, China

9. Research Centre of Infection and Immunology, University of Hong Kong, Hong Kong Special Administrative Region, China

10. State Key Laboratory for Emerging Infectious Diseases, University of Hong Kong, Hong Kong Special Administrative Region, China

11. Division of Host-Microbe Systems and Therapeutics, Department of Pediatrics, University of California, San Diego, La Jolla

12. Menzies Health Institute Queensland, Griffith University, Gold Coast

13. Departments of Infectious Diseases and Pediatrics, Gold Coast Health, Queensland, Australia

Abstract

Abstract Sentinel hospital surveillance was instituted in Australia to detect the presence of pandemic group A Streptococcus strains causing scarlet fever. Genomic and phylogenetic analyses indicated the presence of an Australian GAS emm12 scarlet fever isolate related to United Kingdom outbreak strains. National surveillance to monitor this pandemic is recommended.

Funder

National Health and Medical Research Council of Australia

Wellcome Trust, UK

Chinese Center for Disease Control and Prevention

Department of Health Consultancy Service for Enhancing Laboratory Surveillance of Emerging Infectious Diseases

Research Capability on Antimicrobial Resistance

Queen Mary Hospital Charitable Trust, Hong Kong.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

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