Do dose response thresholds exist for genotoxic alkylating agents?-Reference-Cited by-同舟云学术

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Do dose response thresholds exist for genotoxic alkylating agents?

Published:2005-08-31 Issue:6 Volume:20 Page:389-398
ISSN:1464-3804
Container-title:Mutagenesis
language:en
Short-container-title:

Author:

Jenkins G.J.S.,Doak S.H.,Johnson G.E.,Quick E.,Waters E.M.,Parry J.M.

Publisher

Oxford University Press (OUP)

Subject

Health, Toxicology and Mutagenesis,Genetics (clinical),Toxicology,Genetics

Link

http://academic.oup.com/mutage/article-pdf/20/6/389/3552850/gei054.pdf

Reference75 articles.

1. Schneiderman,M.A., Decoufle,P. and Brown,C.C. (1979) Thresholds for environmental cancer: biologic and statistical considerations. Ann. N. Y. Acad. Sci., 329, 92–130.

2. Lutz,W.K. (1998) Dose response relationships in chemical carcinogenesis, super-position of different mechanisms of activation, resulting in linear-nonlinear curves, practical thresholds, J shapes. Mutat. Res., 405, 117–124.

3. Parry,J.M., Jenkins,G.J.S., Haddad,F., Bourner,R. and Parry,E.M. (2000) In vitro and in vivo extrapolations of genotoxin exposures: consideration of factors which influence dose response thresholds. Mutat. Res., 464, 53–63.

4. Crebelli,R. (2000). Threshold-mediated mechanisms in mutagenesis: implications in the classification and regulation of chemical mutagens. Mutat. Res., 464, 129–135.

5. Speit,G., Autrup,H., Crebelli,R., Henderson,L., Kirsch-Volders,M., Madle,S., Parry,J.M., Sarrif,A.M. and Vrijhof,H. (2000) Thresholds in genetic toxicology—concluding remarks. Mutat. Res., 464, 149–153.

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