Associations Between Antiretroviral Regimen and Changes in Blood Pressure: Results From the D2EFT Study-Reference-Cited by-同舟云学术

Associations Between Antiretroviral Regimen and Changes in Blood Pressure: Results From the D2EFT Study

Published:2024-05-09 Issue: Volume: Page:
ISSN:1058-4838
Container-title:Clinical Infectious Diseases
language:en
Short-container-title:

Author:

Nyein Phyo Pyae¹,Petoumenos Kathy¹,Borok Margaret²,Eriobu Nnakelu³,Kumarasamy Nagalingeswaran⁴,Avihingsanon Anchalee⁵,Azwa Iskandar⁶,Dao Sounkalo⁷,Cisse Mohamed⁸,Dharan Nila J¹,Hanson Josh¹,Matthews Gail V¹

Affiliation:

1. The Kirby Institute, University of New South Wales , Sydney , Australia

2. University of Zimbabwe Clinical Research Centre , Harare , Zimbabwe

3. International Research Center of Excellence (IREC), Institute of Human Virology Nigeria , Abuja , Nigeria

4. VHS Infectious Diseases Medical Centre, Chennai Antiviral Research and Treatment Clinical Research Site (CART CRS) Voluntary Health Services (VHS) , Chennai , India

5. The HIV Netherlands Australia Thailand Research Collaboration (HIV-NAT), Thai Red Cross AIDS Research Centre , Bangkok , Thailand

6. University of Malaya Medical Centre (UMMC) , Kuala Lumpur , Malaysia

7. University Clinical Research Centre (UCRC) , Bamako , Mali

8. Centre de Traitement Ambulatoire de Donka (Hospital de Jour) , Université Gamal Abdel Nasser de Conakry, Conakry , Guinea

Abstract

Abstract In this randomized controlled study, individuals taking dolutegravir+darunavir/ritonavir had greater increases in systolic and diastolic blood pressure than those taking 2 nucleoside reverse-transcriptase inhibitors+darunavir/ritonavir at week-48. The difference remained significant after controlling for confounding factors, including weight gain.

Funder

UNITAID

National Institute of Allergy and Infectious Diseases

National Institutes of Health

National Health and Medical Research Council

ViiV Healthcare

Publisher

Oxford University Press (OUP)

Link

https://academic.oup.com/cid/advance-article-pdf/doi/10.1093/cid/ciae256/58179416/ciae256.pdf

Reference12 articles.

1. Comparison of overall and comorbidity-free life expectancy between insured adults with and without HIV infection, 2000–2016;Marcus;JAMA Netw Open,2020

2. Associations between change in BMI and the risk of hypertension and dyslipidaemia in people receiving integrase strand-transfer inhibitors, tenofovir alafenamide, or both compared with other contemporary antiretroviral regimens: a multicentre, prospective observational study from the RESPOND consortium cohorts;Byonanebye;Lancet HIV,2024

3. More pressure on integrase strand-transfer inhibitors?;Pozniak;Lancet HIV,2024

4. Hypertension in a randomized trial of DTG vs EFV-based ART in pregnant and postpartum women;Hoffman

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Considerations on the Associations Between Antiretroviral Regimen and Changes in Blood Pressure in the D2EFT Study;Clinical Infectious Diseases;2024-06-29

2. Reply to Dr Martinez: Refining Our Understanding of the Association Between Integrase Inhibitor Therapy and Elevations in Blood Pressure;Clinical Infectious Diseases;2024-06-28