Impact of an internet-based insomnia intervention on suicidal ideation and associated correlates in veterans at elevated suicide risk

Author:

Nazem Sarra1,Sun Shengnan23,Barnes Sean M45,Monteith Lindsey L456,Hostetter Trisha A4,Forster Jeri E46,Brenner Lisa A4567ORCID,Galfalvy Hanga89,Haghighi Fatemeh23ORCID

Affiliation:

1. Dissemination and Training Division, National Center for PTSD , Palo Alto, CA , USA

2. Department of Neuroscience, Icahn School of Medicine , New York, NY , USA

3. General Medical Research (GMR), James J. Peters VA Medical Center , Bronx, NY , USA

4. VA Rocky Mountain Mental Illness Research, Education and Clinical Center (MIRECC) , Aurora, CO , USA

5. Department of Psychiatry, University of Colorado School of Medicine , Aurora, CO , USA

6. Department of Physical Medicine and Rehabilitation, University of Colorado School of Medicine , Aurora, Co , USA

7. Department of Neurology, University of Colorado School of Medicine , Aurora, CO , USA

8. Department of Psychiatry, Columbia University , New York, NY , USA

9. Department of Biostatistics, Columbia University , New York, NY , USA

Abstract

Abstract Improving public health approaches to suicide prevention requires scalable evidence-based interventions that can be easily disseminated. Given empirical data supporting the association between insomnia and suicide risk, internet-delivered insomnia interventions are promising candidates to meet this need. The purpose of this study was to examine whether an unguided internet-delivered cognitive-behavioral therapy for insomnia (iCBT-I) improved insomnia severity, suicidal ideation (SI), and suicide risk correlates (depression, post-traumatic stress disorder, anxiety, hostility, belongingness, hopelessness, agitation, irritability, concentration) in a sample of veterans. Secondary data analysis of Operation Enduring Freedom, Operation Iraqi Freedom, and Operation New Dawn veterans (n = 50) with clinically significant insomnia and elevated SI drawn from a larger randomized controlled trial (RCT) of an iCBT-I, Sleep Healthy Using the Internet (SHUTi). Two-sample t-tests or Wilcoxon rank sum tests were used to evaluate between-group differences (SHUTi vs. Insomnia Education Website control) in symptom improvement from baseline to post-intervention. SHUTi participants experienced a significant improvement in insomnia severity (P < .001; d = −1.08) and a non-significant with small (subthreshold medium) effect size reduction of SI (P = .17, d = 0.40), compared to control participants. Significant improvement in hopelessness was observed (medium effect size), with non-significant small to medium effect size reductions in most remaining suicide risk correlates. Self-administered iCBT-I was associated with improvements in insomnia severity in veterans at elevated risk for suicide. These preliminary findings suggest that SI and suicide risk correlates may improve following an iCBT-I intervention, demonstrating the need for future well-powered iCBT-I RCTs targeted for populations at elevated suicide risk.

Funder

Military Suicide Research Consortium

Oxford University Press

Publisher

Oxford University Press (OUP)

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