Animal models of eosinophilic esophagitis-Reference-Cited by-同舟云学术

Animal models of eosinophilic esophagitis

Published:2024-03-20 Issue:2 Volume:116 Page:349-356
ISSN:1938-3673
Container-title:Journal of Leukocyte Biology
language:en
Short-container-title:

Author:

Pilat Jennifer M¹,Jacobse Justin¹²³⁴,Buendia Matthew A⁵,Choksi Yash A¹⁴⁶⁷^ORCID

Affiliation:

1. Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Vanderbilt University Medical Center , 1075 Medical Research Building IV, B-2215 Garland Ave, Nashville, TN 37232 , United States

2. Department of Pediatrics, Willem-Alexander Children's Hospital, Leiden University Medical Center , Albinusdreef 2, 2333 ZA Leiden, the Netherlands

3. Division of Molecular Pathogenesis, Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, 1211 Medical Center Drive , Nashville, TN 37232 , United States

4. Veterans Affairs Tennessee Valley Healthcare System , 1310 24th Ave S, Nashville, TN 37232 , United States

5. Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Vanderbilt University Medical Center , 2200 Children's Way, Nashville, TN 37232 , United States

6. Program in Cancer Biology, School of Medicine, Vanderbilt University , 1075 Medical Research Building IV, B-2215 Garland Ave, Nashville, TN 37232 , United States

7. Center for Mucosal Inflammation and Cancer, Vanderbilt University Medical Center , 1030 Medical Research Building IV, 2215 Garland Ave, Nashville, TN 37232 , United States

Abstract

Abstract Eosinophilic esophagitis is a chronic inflammatory disorder of the esophagus. Over the past 25 yr, great strides have been made toward understanding its pathogenesis, in part due to studies in several types of animal models. The vast majority of these models have been characterized in mice. In this review, we summarize the histopathological features of eosinophilic esophagitis recapitulated by these animal models, as well as discuss their strengths and weaknesses.

Funder

Veterans Affairs Career Development Award

Academy Ter Meulen Grant

Royal Netherlands Academy of Arts and Sciences

Cultural Foundation Grant

Prince Bernhard Cultural Foundation

Vanderbilt Supporting Careers in Research for Interventional Physicians and Surgeons

Publisher

Oxford University Press (OUP)

Link

https://academic.oup.com/jleukbio/advance-article-pdf/doi/10.1093/jleuko/qiae043/57032977/qiae043.pdf

Reference58 articles.