The role of concomitant coronary artery bypass grafting in acute type A aortic dissection complicated by coronary malperfusion

Author:

Pitts Leonard12ORCID,Kofler Markus123,Montagner Matteo12,Heck Roland12,Kurz Stephan Dominik12,Sündermann Simon123,Falk Volkmar1234ORCID,Kempfert Jörg123ORCID

Affiliation:

1. Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum der Charité (DHZC) , Berlin, Germany

2. Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health , Berlin, Germany

3. DZHK (German Centre for Cardiovascular Research) , Berlin, Germany

4. Department of Health Sciences and Technology, Translational Cardiovascular Technologies, Institute of Translational Medicine, Swiss Federal Institute of Technology (ETH) , Zurich, Switzerland

Abstract

Abstract OBJECTIVES Managing acute type A aortic dissection with coronary malperfusion is challenging. This study outlines our revascularization strategy for these patients. METHODS Patients undergoing surgery for acute type A aortic dissection with coronary malperfusion and aortic root involvement from January 2000 to December 2021 were included. Patients were classified using the Neri classification for coronary dissection, including a novel ‘Neri −’ class (no coronary dissection). Patients undergoing revascularization either as a planned or as a bailout strategy due to persisting low cardiac output were compared additionally. RESULTS The cohort comprised 195 patients: 43 (22%) Neri −, 43 (22%) Neri A, 74 (38%) Neri B and 35 (18%) Neri C. Aortic root replacement was mainly performed in 25 Neri C patients (71%; P < 0.001). Concomitant bypass surgery was performed in 4 (9%) of Neri −, 5 (12%) of Neri A, 21 (28%) of Neri B and 32 (91%) of Neri C patients (P < 0.001). Thirty-day mortality was 42% with 21 (49%) Neri −, 12 (28%) Neri A, 30 (41%) Neri B and 19 (54%) Neri C patients (P = 0.087). Bailout revascularization was primarily performed in 11 Neri B patients (69%; P = 0.001) and associated with a higher 30-day mortality of 81% compared to 48% for planned revascularization (P = 0.042). CONCLUSIONS Postoperative outcomes in case of coronary malperfusion are poor, irrespective of the anatomic dissection pattern. The decision for concomitant bypass surgery is crucial but may be considered in Neri C patients combined with aortic root replacement. Bailout revascularization was most common in Neri B and showed dismal outcome.

Publisher

Oxford University Press (OUP)

Reference12 articles.

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