Current challenges in three-dimensional bioprinting heart tissues for cardiac surgery-Reference-Cited by-同舟云学术

Current challenges in three-dimensional bioprinting heart tissues for cardiac surgery

Published:2020-05-11 Issue:3 Volume:58 Page:500-510
ISSN:1010-7940
Container-title:European Journal of Cardio-Thoracic Surgery
language:en
Short-container-title:

Author:

Roche Christopher D¹²³⁴^ORCID,Brereton Russell J L²,Ashton Anthony W¹,Jackson Christopher¹,Gentile Carmine¹³^ORCID

Affiliation:

1. Northern Clinical School of Medicine, University of Sydney, Kolling Institute, St Leonards, Sydney, NSW, Australia

2. Department of Cardiothoracic Surgery, Royal North Shore Hospital, St Leonards, Sydney, NSW, Australia

3. Department of Biomedical Engineering, Faculty of Engineering and IT, University of Technology Sydney (UTS), Ultimo, Sydney, NSW, Australia

4. Department of Cardiothoracic Surgery, University Hospital of Wales, Cardiff, UK

Abstract

Abstract Summary Previous attempts in cardiac bioengineering have failed to provide tissues for cardiac regeneration. Recent advances in 3-dimensional bioprinting technology using prevascularized myocardial microtissues as ‘bioink’ have provided a promising way forward. This review guides the reader to understand why myocardial tissue engineering is difficult to achieve and how revascularization and contractile function could be restored in 3-dimensional bioprinted heart tissue using patient-derived stem cells.

Funder

Sir John Loewenthal Scholarship 2019

Le Gros Legacy Fund New Zealand

Heart Research Australia PhD Scholarship

University of Sydney Kick-Start Grant

University of Sydney Chancellor's Doctoral Incentive Programme Grant

Sydney Medical School Foudation Cardiothoracic Surgery Research Grant

Publisher

Oxford University Press (OUP)

Subject

Cardiology and Cardiovascular Medicine,Pulmonary and Respiratory Medicine,General Medicine,Surgery

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