The Cancer Epitope Database and Analysis Resource (CEDAR)

Author:

Koşaloğlu-Yalçın Zeynep1ORCID,Blazeska Nina1,Vita Randi1,Carter Hannah2,Nielsen Morten34ORCID,Schoenberger Stephen5,Sette Alessandro12,Peters Bjoern12

Affiliation:

1. Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology ,  La Jolla ,  CA , USA

2. Department of Medicine, University of California San Diego , La Jolla ,  CA ,  USA

3. Department of Bio and Health Informatics, Technical University of Denmark ,  Lyngby ,  Denmark

4. Instituto de Investigaciones Biotecnológicas, Universidad Nacional de San Martín , San Martín , Argentina

5. Laboratory of Cellular Immunology, La Jolla Institute for Immunology , La Jolla ,  CA ,  USA

Abstract

Abstract We established The Cancer Epitope Database and Analysis Resource (CEDAR) to catalog all epitope data in the context of cancer. The specific molecular targets of adaptive T cell and B cell immune responses are referred to as epitopes. Epitopes derived from cancer antigens are of high relevance as they are recognized by anti-cancer immune cells. Detailed knowledge of the molecular characteristic of cancer epitopes and associated metadata is relevant to understanding and planning prophylactic and therapeutic applications and accurately characterizing naturally occurring immune responses and cancer immunopathology. CEDAR provides a freely accessible, comprehensive collection of cancer epitope and receptor data curated from the literature and serves as a companion site to the Immune Epitope Database (IEDB), which is focused on infectious, autoimmune, and allergic diseases. CEDAR is freely accessible at https://cedar.iedb.org/.

Funder

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Genetics

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