PlantCircRNA: a comprehensive database for plant circular RNAs

Author:

He Shutian1,Bing Jianhao1,Zhong Yang1,Zheng Xiaoyang1,Zhou Ziyu1,Wang Yifei1,Hu Jiming1,Sun Xiaoyong1ORCID

Affiliation:

1. Agricultural Big Data Research Center, College of Information Science and Engineering, Shandong Agricultural University , Taian 271018 , China

Abstract

Abstract Circular RNAs (circRNAs) represent recently discovered novel regulatory non-coding RNAs. While they are present in many eukaryotes, there has been limited research on plant circRNAs. We developed PlantCircRNA (https://plant.deepbiology.cn/PlantCircRNA/) to fill this gap. The two most important features of PlantCircRNA are (i) it incorporates circRNAs from 94 plant species based on 39 245 RNA-sequencing samples and (ii) it imports the original AtCircDB and CropCircDB databases. We manually curated all circRNAs from published articles, and imported them into the database. Furthermore, we added detailed information of tissue as well as abiotic stresses to the database. To help users understand these circRNAs, the database includes a detection score to measure their consistency and a naming system following the guidelines recently proposed for eukaryotes. Finally, we developed a comprehensive platform for users to visualize, analyze, and download data regarding specific circRNAs. This resource will serve as a home for plant circRNAs and provide the community with unprecedented insights into these mysterious molecule.

Funder

National Natural Science Foundation of China

Project of Shandong Province Higher Educational Program for Introduction and Cultivation of Young Innovative Talents in 2021

Publisher

Oxford University Press (OUP)

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