Astrocyte adenosine deaminase loss increases motor neuron toxicity in amyotrophic lateral sclerosis-Reference-Cited by-同舟云学术

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Astrocyte adenosine deaminase loss increases motor neuron toxicity in amyotrophic lateral sclerosis

Published:2019-01-28 Issue:3 Volume:142 Page:586-605
ISSN:0006-8950
Container-title:Brain
language:en
Short-container-title:

Author:

Allen Scott P¹,Hall Benjamin¹,Castelli Lydia M¹,Francis Laura²,Woof Ryan¹,Siskos Alexandros P³,Kouloura Eirini³,Gray Elizabeth⁴,Thompson Alexander G⁴,Talbot Kevin⁴,Higginbottom Adrian¹,Myszczynska Monika¹,Allen Chloe F¹,Stopford Matthew J¹,Hemingway Jordan¹,Bauer Claudia S¹,Webster Christopher P¹,De Vos Kurt J¹,Turner Martin R⁴,Keun Hector C³,Hautbergue Guillaume M¹,Ferraiuolo Laura¹,Shaw Pamela J¹

Affiliation:

1. Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, 385 Glossop Road, Sheffield, UK

2. The Living Systems Institute, University of Exeter, Stocker Road, Exeter, UK

3. Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, London, UK

4. Nuffield Department of Clinical Neurosciences, Oxford University, John Radcliffe Hospital, West Wing Level 6, Oxford, UK

Funder

Neurocare

Motor Neurone Disease Association Senior Fellowship

MNDA-registered charity

Medical Research Council

Motor Neurone Disease Association Lady Edith Wolfson Senior Clinical Fellowship

Motor Neurone Disease Association

MND Association

NIHR Senior Investigator

FP7 project EuroMotor

Cancer Research UK

Imperial Experimental Cancer Medicine Centre & Cancer Research UK Centre

UK Medical Research Council

Alzheimer's Society

The Sheffield NIHR Biomedical Research Centre

Publisher

Oxford University Press (OUP)

Subject

Neurology (clinical)

Link

http://academic.oup.com/brain/article-pdf/142/3/586/27986478/awy353.pdf

Reference74 articles.

1. p62 positive, TDP-43 negative, neuronal cytoplasmic and intranuclear inclusions in the cerebellum and hippocampus define the pathology of C9orf72-linked FTLD and MND/ALS;Al-Sarraj;Acta Neuropathol,2011

2. Up-regulation of adenosine receptors in the frontal cortex in Alzheimer’s disease;Albasanz;Brain Pathol,2008

3. Can astrocytes be a target for precision medicine?;Allen;Adv Exp Med Biol,2017

4. Altered age-related changes in bioenergetic properties and mitochondrial morphology in fibroblasts from sporadic amyotrophic lateral sclerosis patients;Allen;Neurobiol Aging,2015

5. Superoxide dismutase 1 mutation in a cellular model of amyotrophic lateral sclerosis shifts energy generation from oxidative phosphorylation to glycolysis;Allen;Neurobiol Aging,2014

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