Reduced striatal dopamine synthesis capacity in patients with schizophrenia during remission of positive symptoms

Author:

Avram Mihai123,Brandl Felix124,Cabello Jorge3,Leucht Claudia4,Scherr Martin4,Mustafa Mona3,Leucht Stefan45,Ziegler Sibylle36,Sorg Christian124

Affiliation:

1. Department of Neuroradiology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany

2. TUM-NIC Neuroimaging Center, Klinikum rechts der Isar, Technische Universität München, Munich, Germany

3. Department of Nuclear Medicine, Klinikum rechts der Isar, Technische Universität München, Munich, Germany

4. Department of Psychiatry, Klinikum rechts der Isar, Technische Universität München, Munich, Germany

5. Department of Psychosis Studies, King’s College London, UK

6. Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany

Funder

European Union 7th Framework Programme

TRIMAGE

Publisher

Oxford University Press (OUP)

Subject

Neurology (clinical)

Reference101 articles.

1. Increased striatal dopamine transmission in schizophrenia: confirmation in a second cohort;Abi-Dargham;Am J Psychiatry,1998

2. Increased baseline occupancy of D2 receptors by dopamine in schizophrenia;Abi-Dargham;Proc Natl Acad Sci USA,2000

3. Baseline and amphetamine-stimulated dopamine activity are related in drug-naive schizophrenic subjects;Abi-Dargham;Biol Psychiatry,2009

4. Parallel organization of functionally segregated circuits linking basal ganglia and cortex;Alexander;Ann Rev Neurosci,1986

5. Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database;Allen;Nat Genet,2008

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