Longer and better lives for patients with atrial fibrillation: the 9th AFNET/EHRA consensus conference-Reference-Cited by-同舟云学术

Longer and better lives for patients with atrial fibrillation: the 9th AFNET/EHRA consensus conference

Published:2024-03-30 Issue:4 Volume:26 Page:
ISSN:1099-5129
Container-title:Europace
language:en
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Author:

Linz Dominik¹²^ORCID,Andrade Jason G³⁴^ORCID,Arbelo Elena⁵⁶⁷⁸^ORCID,Boriani Giuseppe⁹^ORCID,Breithardt Guenter¹⁰¹¹^ORCID,Camm A John¹²^ORCID,Caso Valeria¹³^ORCID,Nielsen Jens Cosedis¹⁴^ORCID,De Melis Mirko¹⁵^ORCID,De Potter Tom¹⁶^ORCID,Dichtl Wolfgang¹⁷^ORCID,Diederichsen Søren Zoega¹⁸^ORCID,Dobrev Dobromir¹⁹^ORCID,Doll Nicolas²⁰,Duncker David²¹^ORCID,Dworatzek Elke²²,Eckardt Lars¹¹²³^ORCID,Eisert Christoph²⁴^ORCID,Fabritz Larissa¹¹²⁵²⁶²⁷^ORCID,Farkowski Michal²⁸^ORCID,Filgueiras-Rama David⁷²⁹³⁰^ORCID,Goette Andreas¹¹³¹^ORCID,Guasch Eduard⁶⁷³²^ORCID,Hack Guido³³,Hatem Stéphane³⁴^ORCID,Haeusler Karl Georg¹¹³⁵^ORCID,Healey Jeff S³⁶³⁷^ORCID,Heidbuechel Hein³⁸^ORCID,Hijazi Ziad³⁸³⁹⁴⁰^ORCID,Hofmeister Lucas H⁴¹,Hove-Madsen Leif⁷⁴²⁴³^ORCID,Huebner Thomas²⁴,Kääb Stefan⁸⁴⁴⁴⁵^ORCID,Kotecha Dipak²⁷⁴⁶^ORCID,Malaczynska-Rajpold Katarzyna⁴⁷⁴⁸^ORCID,Merino José Luis⁴⁹^ORCID,Metzner Andreas⁵⁰^ORCID,Mont Lluís⁵⁶⁷^ORCID,Ng Ghulam Andre⁵¹⁵²^ORCID,Oeff Michael¹¹⁵³,Parwani Abdul Shokor⁵⁴^ORCID,Puererfellner Helmut⁵⁵^ORCID,Ravens Ursula¹¹⁵⁶,Rienstra Michiel⁵⁷^ORCID,Sanders Prashanthan⁵⁸^ORCID,Scherr Daniel⁵⁹^ORCID,Schnabel Renate¹¹²⁶⁵⁰^ORCID,Schotten Ulrich¹¹⁶⁰^ORCID,Sohns Christian⁶¹^ORCID,Steinbeck Gerhard¹¹⁶²,Steven Daniel¹¹⁶³^ORCID,Toennis Tobias²⁶⁵⁰^ORCID,Tzeis Stylianos⁶⁴^ORCID,van Gelder Isabelle C⁵⁷^ORCID,van Leerdam Roderick H⁶⁵,Vernooy Kevin¹^ORCID,Wadhwa Manish⁶⁶,Wakili Reza¹¹⁶⁷⁶⁸,Willems Stephan¹¹²⁶⁶⁹^ORCID,Witt Henning²²^ORCID,Zeemering Stef⁶⁰^ORCID,Kirchhof Paulus¹¹²⁶²⁷⁵⁰^ORCID

Affiliation:

1. Department of Cardiology, Maastricht University Medical Center, Cardiovascular Research Institute Maastricht , Maastricht , The Netherlands

2. Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen , Copenhagen , Denmark

3. Division of Cardiology, Vancouver General Hospital , Vancouver , Canada

4. Montreal Heart Institute , Montreal , Canada

5. Institut Clínic Cardiovascular, Hospital Clinic, Universitat de Barcelona , Barcelona, Catalonia , Spain

6. Institut d’Investigació August Pi i Sunyer (IDIBAPS) , Barcelona, Catalonia , Spain

7. Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV) , Madrid , Spain

8. European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart—ERN GUARD-Heart

9. Cardiology Division, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Polyclinic of Modena , Modena , Italy

10. Department of Cardiovascular Medicine, University Hospital , Münster , Germany

11. Atrial Fibrillation NETwork (AFNET) , Muenster , Germany

12. Cardiology Clinical Academic Group, Molecular and Clinical Sciences Institute, St. George's University of London , London , UK

13. Stroke Unit, Santa Maria della Misericordia Hospital, University of Perugia , Perugia , Italy

14. Department of Cardiology, Aarhus University Hospital and Department of Clinical Medicine , Aarhus University, Aarhus , Denmark

15. Bakken Research Center , Maastricht , The Netherlands

16. Cardiovascular Center, OLV Hospital , Aalst , Belgium

17. Department of Internal Medicine III, Cardiology and Angiology, Medical University Innsbruck , Innsbruck , Austria

18. Department of Cardiology, Copenhagen University Hospital—Rigshospitalet , Copenhagen , Denmark

19. Institute of Pharmacology, Faculty of Medicine, University Hospital Essen, University Duisburg-Essen , Essen , Germany

20. Department of Cardiac Surgery, Schüchtermann-Klinik , Bad Rothenfelde , Germany

21. Hannover Heart Rhythm Center, Department of Cardiology and Angiology, Hannover Medical School , Hannover , Germany

22. Pfizer Pharma GmbH , Berlin , Germany

23. Department of Cardiology II—Electrophysiology, University Hospital Münster , Münster , Germany

24. Preventicus GmbH , Jena , Germany

25. University Center of Cardiovascular Science, UHZ, UKE , Hamburg , Germany

26. German Centre for Cardiovascular Research (DZHK), Partner Site: Hamburg/Kiel/Lübeck , Hamburg , Germany

27. Institute of Cardiovascular Sciences, University of Birmingham , Edgbaston, Birmingham , UK

28. Department of Cardiology, Ministry of Interior and Administration, National Medical Institute , Warsaw , Poland

29. Centro Nacional de Investigaciones Cardiovasculares (CNIC), Novel Arrhythmogenic Mechanisms Program , Madrid , Spain

30. Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Cardiovascular Institute , C/ Profesor Martín Lagos, Madrid , Spain

31. Department of Cardiology and Intensive Care Medicine, St Vincenz-Hospital Paderborn , Paderborn , Germany

32. Clinic Barcelona, University of Barcelona , Barcelona , Spain

33. Bristol-Myers Squibb GmbH & Co. KGaA , Munich , Germany

34. IHU ICAN, Hospital Pitié-Salpêtrière , Paris , France

35. Department of Neurology, Universitätsklinikum Würzburg (UKW) , Würzburg , Germany

36. Division of Cardiology, McMaster University , Hamilton, Ontario , Canada

37. Population Health Research Institute , Hamilton, Ontario , Canada

38. Antwerp University Hospital, Cardiovascular Sciences, University of Antwerp , Antwerp , Belgium

39. Department of Medical Sciences, Cardiology, Uppsala University , Uppsala , Sweden

40. Uppsala Clinical Research Center, Uppsala University , Uppsala , Sweden

41. Global Medical Affairs Bayer AG , Berlin , Germany

42. Biomedical Research Institute Barcelona (IIBB-CSIC) , Barcelona , Spain

43. IR Sant Pau, Hospital de Sant Pau , Barcelona , Spain

44. Department of Medicine I, University Hospital, LMU Munich , Munich , Germany

45. German Centre for Cardiovascular Research (DZHK), Partner Site Munich, Munich Heart Alliance , Munich , Germany

46. NIHR Birmingham Biomedical Research Centre, University Hospitals Birmingham NHS Trust , Birmingham , UK

47. Lister Hospital, East and North Hertfordshire NHS Trust , Stevenage , UK

48. Royal Brompton Hospital, Guy’s and St Thomas’ NHS Foundation Trust , London , UK

49. La Paz University Hospital, IdiPaz, Autonomous University of Madrid , Madrid , Spain

50. Department of Cardiology, University Heart & Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf , Martinistr. 52, Hamburg , Germany

51. Department of Cardiovascular Sciences, University of Leicester , Leicester , UK

52. NIHR Leicester Biomedical Research Centre , Leicester , UK

53. Cardiology Department, Medizinische Hochschule Brandenburg , Brandenburg/Havel , Germany

54. Department of Cardiology, Deutsches Herzzentrum der Charité (CVK) , Berlin , Germany

55. Cardiological Department, Ordensklinikum Linz Elisabethinen , Linz , Austria

56. Institute of Experimental Cardiovascular Medicine, University Clinic Freiburg , Freiburg , Germany

57. University Medical Center Groningen, University of Groningen , Groningen , The Netherlands

58. Centre for Heart Rhythm Disorders, University of Adelaide and Royal Adelaide Hospital , Adelaide , Australia

59. Division of Cardiology, Medical University of Graz , Graz , Austria

60. Departments of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University , Maastricht , The Netherlands

61. Herz- und Diabeteszentrum Nordrhein-Westfalen, Universitätsklinik der Ruhr-Universität Bochum, Klinik für Elektrophysiologie—Rhythmologie , Bad Oeynhausen , Germany

62. Center for Cardiology at Clinic Starnberg , Starnberg , Germany

63. Heart Center, Department of Electrophysiology, University Hospital Cologne , Cologne , Germany

64. Cardiology Department, Mitera Hospital , Athens , Greece

65. Royal Philips , Amsterdam , The Netherlands

66. Medical Office, Philips Ambulatory Monitoring and Diagnostics , San Diego, CA , USA

67. Department of Medicine and Cardiology, Goethe University , Frankfurt , Germany

68. German Centre for Cardiovascular Research (DZHK) , Partner Site Rhine-Main , Germany

69. Asklepios Hospital St. Georg, Department of Cardiology and Internal Care Medicine, Faculty of Medicine, Semmelweis University Campus , Hamburg , Germany

Abstract

Abstract Aims Recent trial data demonstrate beneficial effects of active rhythm management in patients with atrial fibrillation (AF) and support the concept that a low arrhythmia burden is associated with a low risk of AF-related complications. The aim of this document is to summarize the key outcomes of the 9th AFNET/EHRA Consensus Conference of the Atrial Fibrillation NETwork (AFNET) and the European Heart Rhythm Association (EHRA). Methods and results Eighty-three international experts met in Münster for 2 days in September 2023. Key findings are as follows: (i) Active rhythm management should be part of the default initial treatment for all suitable patients with AF. (ii) Patients with device-detected AF have a low burden of AF and a low risk of stroke. Anticoagulation prevents some strokes and also increases major but non-lethal bleeding. (iii) More research is needed to improve stroke risk prediction in patients with AF, especially in those with a low AF burden. Biomolecules, genetics, and imaging can support this. (iv) The presence of AF should trigger systematic workup and comprehensive treatment of concomitant cardiovascular conditions. (v) Machine learning algorithms have been used to improve detection or likely development of AF. Cooperation between clinicians and data scientists is needed to leverage the potential of data science applications for patients with AF. Conclusions Patients with AF and a low arrhythmia burden have a lower risk of stroke and other cardiovascular events than those with a high arrhythmia burden. Combining active rhythm control, anticoagulation, rate control, and therapy of concomitant cardiovascular conditions can improve the lives of patients with AF.

Funder

AFNET

EHRA

MAESTRIA

Publisher

Oxford University Press (OUP)

Link

https://academic.oup.com/europace/article-pdf/26/4/euae070/57346253/euae070.pdf

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