Staurosporine targets the Hippo pathway to inhibit cell growth

Author:

Ma Xueyan1,Li Peixue1,Chen Peihao2,Li Jinhui1,Huang Hongling1,Wang Chao1,Li Wenjing3,Ding Jianping3,Zhao Yun14,Yu Fa-Xing5,Qi Xiangbing2,Zhang Lei14

Affiliation:

1. State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China

2. National Institute of Biological Sciences, Beijing, China

3. National Center for Protein Science Shanghai, State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China

4. School of Life Science and Technology, ShanghaiTech University, Shanghai, China

5. Children’s Hospital and Institutes of Biomedical Sciences, Fudan University, Shanghai, China

Publisher

Oxford University Press (OUP)

Subject

Cell Biology,Genetics,Molecular Biology,General Medicine

Reference12 articles.

1. YAP1 increases organ size and expands undifferentiated progenitor cells;Camargo;Curr. Biol.,2007

2. Staurosporine-induced neuronal death: multiple mechanisms and methodological implications;Deshmukh;Cell Death Differ.,2000

3. Pharmacological targeting of kinases MST1 and MST2 augments tissue repair and regeneration;Fan;Sci. Transl. Med.,2016

4. Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP;Liu-Chittenden;Genes Dev.,2012

5. Mechanisms of Hippo pathway regulation;Meng;Genes Dev.,2016

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