Consistent Detection of 2019 Novel Coronavirus in Saliva-Reference-Cited by-全球学者库

Consistent Detection of 2019 Novel Coronavirus in Saliva

Published:2020-02-12 Issue:15 Volume:71 Page:841-843
ISSN:1058-4838
Container-title:Clinical Infectious Diseases
language:en
Short-container-title:

Author:

To Kelvin Kai-Wang¹²³,Tsang Owen Tak-Yin⁴,Yip Cyril Chik-Yan¹²,Chan Kwok-Hung¹,Wu Tak-Chiu⁵,Chan Jacky Man-Chun⁴,Leung Wai-Shing⁴,Chik Thomas Shiu-Hong⁴,Choi Chris Yau-Chung⁴,Kandamby Darshana H⁶,Lung David Christopher⁷,Tam Anthony Raymond⁸,Poon Rosana Wing-Shan¹²,Fung Agnes Yim-Fong¹,Hung Ivan Fan-Ngai⁸,Cheng Vincent Chi-Chung¹²,Chan Jasper Fuk-Woo¹²³,Yuen Kwok-Yung¹²³

Affiliation:

1. State Key Laboratory for Emerging Infectious Diseases, Department of Microbiology, Carol Yu Centre for Infection, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China

2. Department of Microbiology, Queen Mary Hospital, Hong Kong Special Administrative Region, China

3. Department of Clinical Microbiology and Infection Control, The University of Hong Kong–Shenzhen Hospital, Shenzhen, China

4. Department of Medicine and Geriatrics, Princess Margaret Hospital, Hong Kong Special Administrative Region, China

5. Department of Medicine, Queen Elizabeth Hospital, Hong Kong Special Administrative Region, China

6. Intensive Care Unit, Princess Margaret Hospital, Hong Kong Special Administrative Region, China

7. Department of Pathology, Queen Elizabeth Hospital, Hong Kong Special Administrative Region, China

8. Department of Medicine, Queen Mary Hospital, Hong Kong Special Administrative Region, China

Abstract

Abstract The 2019 novel coronavirus (2019-nCoV) was detected in the self-collected saliva of 91.7% (11/12) of patients. Serial saliva viral load monitoring generally showed a declining trend. Live virus was detected in saliva by viral culture. Saliva is a promising noninvasive specimen for diagnosis, monitoring, and infection control in patients with 2019-nCoV infection.

Funder

Theme-Based Research Scheme of the Research Grants Council

Sanming Project of Medicine in Shenzhen

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

Link

http://academic.oup.com/cid/advance-article-pdf/doi/10.1093/cid/ciaa149/32518265/ciaa149.pdf

Reference12 articles.

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2. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster;Chan;Lancet,2020