Clinical Course and Outcome of Human Monkeypox in Nigeria

Author:

Ogoina Dimie1ORCID,Iroezindu Michael2,James Hendris Izibewule1,Oladokun Regina3,Yinka-Ogunleye Adesola4,Wakama Paul5,Otike-odibi Bolaji6,Usman Liman Muhammed7,Obazee Emmanuel6,Aruna Olusola8,Ihekweazu Chikwe4

Affiliation:

1. Infectious Disease Unit, Niger Delta University Teaching Hospital, Okolobiri, Bayelsa, Nigeria

2. Infectious Disease Unit, Federal Medical Centre Owerri/University of Nigeria Teaching Hospital, Enugu, Nigeria

3. Paediatric Infectious Disease Unit, University College Hospital, Ibadan, Oyo State, Nigeria

4. Nigerian Centre for Disease Control, Abuja, Federal Capital Territory, Nigeria

5. Nigerian Prison Services, Port Harcourt, Rivers State, Nigeria

6. Department of Medicine, University of Port Harcourt Teaching Hospital, Port Harcourt, Rivers State, Nigeria

7. Ministry of Health, Nasarawa, Nasarawa State, Nigeria

8. Global Public Health Department, Public Health England, London, United Kingdom

Abstract

Abstract In a retrospective review of hospital records of 40 human monkeypox cases from Nigeria, the majority developed fever and self-limiting vesiculopustular skin eruptions. Five deaths were reported. Compared to human immunodeficiency virus (HIV)–negative cases, HIV type 1–coinfected cases had more prolonged illness, larger lesions, and higher rates of both secondary bacterial skin infections and genital ulcers.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

Reference16 articles.

1. Outbreak of human monkeypox in Nigeria in 2017–18: a clinical and epidemiological report;Yinka-Ogunleye,2019

2. Human monkeypox, 1970-79;Breman;Bull World Health Organ,1980

3. The 2017 human monkeypox outbreak in Nigeria—report of outbreak experience and response in the Niger Delta University Teaching Hospital, Bayelsa State, Nigeria;Ogoina;PLoS One,2019

4. Human monkeypox: clinical features of 282 patients;Jezek;J Infect Dis,1987

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