Real-Time Whole Genome Sequencing to Guide Patient-Tailored Therapy of Severe Acute Respiratory Syndrome Coronavirus 2 Infection-Reference-Cited by-同舟云学术

Real-Time Whole Genome Sequencing to Guide Patient-Tailored Therapy of Severe Acute Respiratory Syndrome Coronavirus 2 Infection

Published:2022-11-03 Issue:6 Volume:76 Page:1125-1128
ISSN:1058-4838
Container-title:Clinical Infectious Diseases
language:en
Short-container-title:

Author:

Snell Luke B¹^ORCID,Alcolea-Medina Adela¹,Charalampous Themoula¹,Alder Christopher¹,Williams Tom G S¹,Flaviani Flavia²,Batra Rahul¹,Bakrania Prijay³,Thangarajah Rajeni¹³,Neil Stuart J D⁴,van Nispen tot Pannerden Claire¹,Botgros Alina¹,Aarons Emma¹,Douthwaite Samuel T¹,Edgeworth Jonathan D¹,Nebbia Gaia¹⁴

Affiliation:

1. Department of Infection, Guy's and St. Thomas' NHS Foundation Trust , London , UK

2. National Institute for Health Research Biomedical Research Centre, Guy's and St. Thomas' NHS Foundation Trust , London , UK

3. Department of Pharmacy, Guy's and St Thomas’ NHS Foundation Trust , London , UK

4. Department of Infectious Diseases, King's College London , United Kingdom

Abstract

Abstract The management of coronavirus disease 2019 has become more complex due to the expansion of available therapies. The presence of severe acute respiratory syndrome coronavirus 2 variants and mutations further complicates treatment due to their differing susceptibilities to therapies. Here we outline the use of real-time whole genome sequencing to detect persistent infection, evaluate for mutations confering resistance to treatments, and guide treatment decisions.

Funder

Medical Research Council

(MRC)

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

Link

https://academic.oup.com/cid/advance-article-pdf/doi/10.1093/cid/ciac864/47632280/ciac864.pdf

Reference20 articles.

1. A living WHO guideline on drugs for covid-19;Agarwal;BMJ,2020

2. Combined epidemiological and genomic analysis of nosocomial SARS-CoV-2 infection early in the pandemic and the role of unidentified cases in transmission;Snell;Clin Microbiol Infect,2022

3. Rapid genome sequencing in hospitals to identify potential vaccine-escape SARS-CoV-2 variants;Snell;Lancet Infect Dis,2021

4. Analytical validity of nanopore sequencing for rapid SARS-CoV-2 genome analysis;Bull;Nat Commun,2020

5. SARS-CoV-2 evolution during treatment of chronic infection;Kemp;Nature,2021

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