Risk of Long COVID in People Infected With Severe Acute Respiratory Syndrome Coronavirus 2 After 2 Doses of a Coronavirus Disease 2019 Vaccine: Community-Based, Matched Cohort Study-Reference-Cited by-同舟云学术

Risk of Long COVID in People Infected With Severe Acute Respiratory Syndrome Coronavirus 2 After 2 Doses of a Coronavirus Disease 2019 Vaccine: Community-Based, Matched Cohort Study

Published:2022-09-01 Issue:9 Volume:9 Page:
ISSN:2328-8957
Container-title:Open Forum Infectious Diseases
language:en
Short-container-title:

Author:

Ayoubkhani Daniel¹²^ORCID,Bosworth Matthew L¹,King Sasha³,Pouwels Koen B⁴⁵,Glickman Myer¹,Nafilyan Vahé¹⁶^ORCID,Zaccardi Francesco²,Khunti Kamlesh²^ORCID,Alwan Nisreen A⁷⁸⁹^ORCID,Walker A Sarah⁴¹⁰

Affiliation:

1. Health Analysis and Life Events Division, Office for National Statistics , Newport , United Kingdom

2. Leicester Real World Evidence Unit, Diabetes Research Centre, University of Leicester , Leicester , United Kingdom

3. Methodology and Quality Directorate, Office for National Statistics , London , United Kingdom

4. National Institute for Health Research Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, University of Oxford , Oxford , United Kingdom

5. Health Economics Research Centre, Nuffield Department of Population Health, University of Oxford , Oxford , United Kingdom

6. Faculty of Public Health, Environment and Society, London School of Hygiene and Tropical Medicine , London , United Kingdom

7. School of Primary Care, Population Sciences and Medical Education, Faculty of Medicine, University of Southampton , Southampton , United Kingdom

8. National Institute for Health Research Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust , Southampton , United Kingdom

9. National Institute for Health Research Applied Research Collaboration Wessex , Southampton , United Kingdom

10. Nuffield Department of Medicine, University of Oxford , Oxford , United Kingdom

Abstract

Abstract We investigated long COVID incidence by vaccination status in a random sample of UK adults from April 2020 to November 2021. Persistent symptoms were reported by 9.5% of 3090 breakthrough severe acute respiratory syndrome coronavirus 2 infections and 14.6% of unvaccinated controls (adjusted odds ratio, 0.59 [95% confidence interval, .50–.69]), emphasizing the need for public health initiatives to increase population-level vaccine uptake.

Funder

NIHR

Huo Family Foundation

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Link

https://academic.oup.com/ofid/advance-article-pdf/doi/10.1093/ofid/ofac464/45799936/ofac464.pdf

Reference14 articles.

1. Prevalence of ongoing symptoms following coronavirus (COVID-19) infection in the UK: 6 January 2022;Office for National Statistics

2. SARS-CoV-2 anti-spike IgG antibody responses after second dose of ChAdOx1 or BNT162b2 and correlates of protection in the UK general population;Wei;medRxiv [Preprint],2022