Diagnostic and Therapeutic Challenges in Disseminated<i>Mycobacterium colombiense</i>Infection Caused by Interferon-γ Neutralizing Autoantibodies-Reference-Cited by-同舟云学术

Diagnostic and Therapeutic Challenges in DisseminatedMycobacterium colombienseInfection Caused by Interferon-γ Neutralizing Autoantibodies

Published:2023-01-27 Issue:2 Volume:10 Page:
ISSN:2328-8957
Container-title:Open Forum Infectious Diseases
language:en
Short-container-title:

Author:

Matono Takashi¹^ORCID,Suzuki Shotaro¹,Yamate Ryosuke¹,Nakamura Kenichi²,Sakagami Takuro³

Affiliation:

1. Department of Infectious Diseases, Aso Iizuka Hospital , Fukuoka , Japan

2. Department of General Internal Medicine, Aso Iizuka Hospital , Fukuoka , Japan

3. Department of Respiratory Medicine, Faculty of Life Sciences, Kumamoto University , Kumamoto , Japan

Abstract

AbstractAdult-onset immunodeficiency due to interferon-γ-neutralizing autoantibodies (nIFNγ-autoAbs) can remain underdiagnosed. We present a case of severe Mycobacterium colombiense infection with nIFNγ-autoAbs. To ensure early diagnosis, clinicians should have a high index of suspicion in patients of Asian descent with opportunistic infections and perform QuantiFERON-TB assay for disease screening.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Link

https://academic.oup.com/ofid/advance-article-pdf/doi/10.1093/ofid/ofad035/48931294/ofad035.pdf

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