#AMRrounds: a systematic educational approach for navigating bench to bedside antimicrobial resistance

Author:

Liu Elaine1,Prinzi Andrea M2ORCID,Borjan Jovan3,Aitken Samuel L4ORCID,Bradford Patricia A5,Wright William F6ORCID

Affiliation:

1. Division of Pharmacy and Division of Infectious Diseases, The Johns Hopkins Bayview Medical Center , 5200 Eastern Avenue, Baltimore, MD , USA

2. US Medical Affairs, bioMérieux , Salt Lake City, UT 84104 , USA

3. Division of Pharmacy, The University of Texas MD Anderson Cancer Center , Houston, TX , USA

4. Department of Pharmacy, Michigan Medicine , Ann Arbor, MI , USA

5. Antimicrobial Development Specialists LLC , Nyack, NY , USA

6. Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine , 733 North Broadway, Baltimore, MD , USA

Abstract

Abstract Antimicrobial resistance (AMR) continues to serve as a major global health crisis. Clinicians practising in this modern era are faced with ongoing challenges in the therapeutic management of patients suffering from antimicrobial-resistant infections. A strong educational understanding and synergistic application of clinical microbiology, infectious disease and pharmacological concepts can assist the adventuring clinician in the navigation of such cases. Important items include mobilizing laboratory testing for pathogen identification and susceptibility data, harnessing an understanding of intrinsic pathogen resistance, acknowledging epidemiological resistance trends, recognizing acquired AMR mechanisms, and consolidating these considerations when constructing an ideal pharmacological plan. In this article, we outline a novel framework by which to systematically approach clinical AMR, encourage AMR-related education and optimize therapeutic decision-making in AMR-related illnesses.

Publisher

Oxford University Press (OUP)

Subject

Microbiology (medical),Infectious Diseases,Immunology and Allergy,Microbiology,Immunology

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