Affiliation:
1. Zhejiang University School of Medicine Department of Thoracic Surgery, the First Affiliated Hospital, , Hangzhou, 310003, China
2. the Second Hospital of Yinzhou Department of Plastic Surgery, , Ningbo, 315000, China
3. Key Laboratory of Clinical Evaluation Technology for Medical Device of Zhejiang Province , Hangzhou, 310003, China
Abstract
Abstract
OBJECTIVES
The application of video-assisted thoracoscopic surgery (VATS) for relatively large mediastinal tumors (≥5.0 cm) has been a subject of debate, and few studies have investigated the subxiphoid approach VATS in different tumour size categories. The study aims to compare the efficacy of subxiphoid approach VATS for achieving curative outcomes based on tumour size categories (<3.0 cm, 3.0∼4.9 cm, and 5.0∼10.0 cm).
METHODS
A total of 165 patients with anterior mediastinal tumors who underwent surgery at our hospital between January 2018 and July 2022 were consecutively enrolled, categorized according to tumour size—Group A (<3.0 cm): 58, Group B (3.0∼4.9 cm): 70, Group C (5.0∼10.0 cm): 37. Clinical baseline data, intraoperative and postoperative outcomes, and postoperative complications were analyzed.
RESULTS
The study revealed significant differences in operation time among the three groups (Group A: 103.4 ± 36.1, Group B: 106.4 ± 35.2, Group C: 127.4 ± 44.8, P < 0.05) as well as in the volume of drainage (Group A: 273.3 ± 162.0, Group B: 411.9 ± 342.6, Group C: 509.7 ± 543.7, P < 0.05). However, no differences were seen in blood loss, drainage duration, postoperative hospital stay and duration of postoperative oral analgesics. Additionally, the incidence of postoperative complications did not exhibit significant differences across these groups.
CONCLUSIONS
Subxiphoid approach VATS is considered as a feasible and safe surgical method for large-sized anterior mediastinal tumors (5.0–10.0 cm) with no invasion to the surrounding tissues and organs.
Publisher
Oxford University Press (OUP)