Inflammatory Bowel Disease Management During the COVID-19 Outbreak: The Ten Do’s and Don’ts from the ECCO-COVID Taskforce

Author:

Magro F1ORCID,Rahier J-F2,Abreu C3,MacMahon E4,Hart A5,van der Woude C J6,Gordon H7,Adamina M8,Viget N9,Vavricka S10,Kucharzik T11,Leone S12,Siegmund B13ORCID,Danese S1415,Peyrin-Biroulet L1617

Affiliation:

1. Department of Biomedicine, Unit of Pharmacology and Therapeutics, Faculty of Medicine, University of Porto, Porto, Portugal; Department of Gastroenterology, Centro Hospitalar de São João, Porto, Portugal; Department of Clinical Pharmacology Centro Hospitalar de São João, Porto, Portugal

2. CHU UCL Namur, Université catholique de Louvain, service de Hépato-gastroentérologie, Yvoir, Belgium

3. Infectious Diseases Service, Centro Hospitalar Universitário São João, Porto, Portugal; Instituto de Inovação e Investigação em Saúde (I3s), Faculty of Medicine, Department of Medicine, University of Porto, Portugal

4. Department of Infectious Diseases, Guy’s and St Thomas’ NHS Foundation Trust, London, UK

5. IBD Unit, St Mark’s Hospital, London, UK

6. Department of Gastroenterology and Hepatology, Erasmus Medical Center, Rotterdam, The Netherlnads

7. Department of Gastroenterology, Royal London Hospital, Barts Health NHS Trust, London, UKCentre for Immunobiology, The Blizard Institute, Barts and the London School of Medicine, Queen Mary University of London, London, UK

8. Department of Surgery, Cantonal Hospital Winterthur, Winterthur, Switzerland

9. Department of Infectious Diseases, Tourcoing Hospital, Tourcoing, France

10. Center for Gastroenterology and Hepatology, Zürich, Switzerland

11. Lüneburg Hospital, University of Hamburg, Department of Gastroenterology, Lüneburg, Germany

12. EFCCA, European Federation of Crohn’s and Ulcerative Colitis Associations, Brussels, Belgium

13. Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Medizinische Klinik für Gastroenterologie, Infektiologie und Rheumatologie, Berlin, Germany

14. IBD Center, Department of Gastroenterology, Humanitas Clinical and Research Center- IRCCS-, Rozzano, Milan, Italy

15. Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy

16. Department of Gastroenterology, Nancy University Hospital, Vandoeuvre-Les-Nancy, France

17. Inserm NGERE U1256, Lorraine University, Vandoeuvre-Les-Nancy, France

Abstract

Abstract Our knowledge of COVID-19 is changing and evolving rapidly, with novel insights and recommendations, almost on a daily basis. It behooves the medical community to provide updated information on a regular basis, on best practice to facilitate optimal care of infected patients and on appropriate advice for the general population. This is particularly important in the case of patients with chronic conditions, such as inflammatory bowel disease [IBD]. In this review, we have compiled existing evidence on the impact of COVID-19 in IBD patients and provide guidance on the most appropriate care to adopt during the pandemic. Our review highlights that IBD, per se, is not a risk factor for COVID-19. However, all IBD patients with symptoms should be tested for SARS-CoV-2 and the procedures for disease management should be carefully adapted: [i] in SARS-CoV-2-positive IBD patients, medical treatments should be re-evaluated [with a particular focus on corticosteroids] always with the purpose of treating active disease and maintaining remission; [ii] non-urgent surgeries and endoscopic procedures should be postponed for all patients; [iii] online consultancy should be implemented; and [iv] hospitalization and surgery should be limited to life-threatening situations.

Funder

ECCO

IOIBD

Publisher

Oxford University Press (OUP)

Subject

Gastroenterology,General Medicine

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