ECCO Guidelines on Therapeutics in Crohn’s Disease: Surgical Treatment

Author:

Adamina Michel12,Bonovas Stefanos34ORCID,Raine Tim5,Spinelli Antonino6,Warusavitarne Janindra7,Armuzzi Alessandro8,Bachmann Oliver9ORCID,Bager Palle10,Biancone Livia11,Bokemeyer Bernd12,Bossuyt Peter13ORCID,Burisch Johan14ORCID,Collins Paul15,Doherty Glen16,El-Hussuna Alaa17,Ellul Pierre18,Fiorino Gionata34ORCID,Frei-Lanter Cornelia19,Furfaro Federica4,Gingert Christian20,Gionchetti Paolo21,Gisbert Javier P22,Gomollon Fernando23,González Lorenzo Marien3,Gordon Hannah24,Hlavaty Tibor25,Juillerat Pascal26ORCID,Katsanos Konstantinos27,Kopylov Uri28,Krustins Eduards29,Kucharzik Torsten30,Lytras Theodore31ORCID,Maaser Christian32,Magro Fernando33ORCID,Marshall John Kenneth34,Myrelid Pär35,Pellino Gianluca36,Rosa Isadora37,Sabino Joao38,Savarino Edoardo39,Stassen Laurents40,Torres Joana41,Uzzan Mathieu42,Vavricka Stephan43,Verstockt Bram44ORCID,Zmora Oded45

Affiliation:

1. Department of Surgery, Cantonal Hospital Winterthur, Winterthur, Switzerland

2. University of Basel, Basel, Switzerland

3. Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy

4. IBD Center, Humanitas Clinical and Research Center, Milan, Italy

5. Department of Gastroenterology, Addenbrooke’s Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK

6. Humanitas Clinical and Research Center, Division of Colon and Rectal Surgery, Humanitas University, Department of Biomedical Sciences, Milan, Italy

7. Imperial College London, Department of Surgery and Cancer, St Mark’s Hospital, Department of Gastroenterology, London, UK

8. IBD Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS - Universita’ Cattolica del Sacro Cuore, Rome, Italy

9. Department of Internal Medicine I, Siloah St Trudpert Hospital, Pforzheim, Germany

10. Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark

11. Department of Systems Medicine, University ‘Tor Vergata’ of Rome, Rome, Italy

12. Gastroenterology Practice Minden, Minden, Germany

13. Imelda GI Clinical Research Centre, Imelda General Hospital, Bonheiden, Belgium

14. Gastrounit, Medical Division, Hvidovre Hospital, University of Copenhagen, Copenhagen, Denmark

15. Department of Gastroenterology, Royal Liverpool University Hospital, Liverpool, UK

16. Department of Gastroenterology and Centre for Colorectal Disease, St Vincent’s University Hospital, Dublin, Ireland

17. Department of Surgery, Aalborg University Hospital, Aalborg, Denmark

18. Department of Medicine, Division of Gastroenterology, Mater Dei Hospital, Msida, Malta

19. Department of Surgery, Hospital Zollikerberg, Zollikerberg Zürich, Switzerland

20. Visceral Surgery, Cantonal Hospital Winterthur, Winterthur, Switzerland; Department of Human Medicine, Faculty of Health, University of Witten/Herdecke, Witten, Germany

21. IBD Unit, DIMEC, University of Bologna, Bologna, Italy

22. Gastroenterology Unit, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa [IIS-IP], Universidad Autónoma de Madrid, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas [CIBEREHD], Madrid, Spain

23. IBD UNIT, Hospital Clíico Universitario ‘Lozano Blesa’, IIS Aragón, CIBEREHD, Zaragoza, Spain

24. Department of Gastroenterology, Barts Health NHS Trust, Royal London Hospital, London, UK

25. Fifth Department of Internal Medicine, Sub-department of Gastroenterology and Hepatology, University Hospital Bratislava and Faculty of Medicine, Comenius University Bratislava, Slovakia

26. Clinic for Visceral Surgery and Medicine, Inselspital, University Hospital of Bern, Bern, Switzerland

27. Department of Gastroenterology and Hepatology, University and Medical School of Ioannina, Ioannina, Greece

28. Department of Gastroenterology, Tel-HaShomer Sheba Medical Center, Ramat Gan, Israel; and Sackler Medical School, Tel Aviv, Israel

29. Department of Gastroenterology, Hepatology and Nutrition, Pauls Stradins Clinical University Hospital, Department of Internal Medicine, Riga Stradiņš University, Riga, Latvia

30. Department of Internal Medicine and Gastroenterology, Hospital Lüneburg, Lüneburg, Germany

31. National Public Health Organization, Athens, Greece

32. Outpatients Department of Gastroenterology, Hospital Lüneburg, Lüneburg, Germany

33. Department of Pharmacology and Therapeutics; Institute for Molecular and Cell Biology, University of Porto, Faculty of Medicine, Porto, Portugal

34. Department of Medicine [Division of Gastroenterology] and Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, ON, Canada

35. Department of Surgery, and Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden

36. Department of Advanced Medical and Surgical Sciences, Universitá degli Studi della Campania ‘Luigi Vanvitelli’, Naples, Italy

37. Department of Gastroenterology, IPOLFG, Lisbon, Portugal

38. Department of Gastroenterology and Hepatology, University Hospitals, KU Leuven, Leuven, Belgium

39. Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy

40. Department of General Surgery, Maastricht University Medical Centre+, Maastricht, The Netherlands

41. Department of Gastroenterology, Hospital Beatriz Ângelo, Loures, Portugal

42. Department of Gastroenterology, IBD unit, Beaujon Hospital, APHP, Clichy, France

43. Division of Gastroenterology and Hepatology, University Hospital, Zürich, Switzerland

44. Department of Gastroenterology and Hepatology, University Hospitals Leuven, KU Leuven, Leuven, Belgium, and Department of Chronic Diseases, Metabolism and Ageing, TARGID - IBD, KU Leuven, Leuven, Belgium

45. Department of Surgery, Shamir Medical Center [Assaf Harofe], Tel Aviv, Israel

Abstract

Abstract This article is the second in a series of two publications relating to the European Crohn’s and Colitis Organisation [ECCO] evidence-based consensus on the management of Crohn’s disease. The first article covers medical management; the present article addresses surgical management, including preoperative aspects and drug management before surgery. It also provides technical advice for a variety of common clinical situations. Both articles together represent the evidence-based recommendations of the ECCO for Crohn’s disease and an update of previous guidelines.

Funder

European Crohn’s and Colitis Organisation

Publisher

Oxford University Press (OUP)

Subject

Gastroenterology,General Medicine

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