Psychological stress, the central nervous system and arrhythmias

Author:

Lambiase P D1,Garfinkel S N2,Taggart P1

Affiliation:

1. UCL Institute of Cardiovascular Science & Barts Heart Centre, Rayne Institute , 5 University Street , London WC1E 6JF, UK

2. UCL Institute of Cognitive Neuroscience

Abstract

Summary This review highlights the links between psychological stress and the neurocircuitry of cardiac–brain interactions leading to arrhythmias. The role of efferent and afferent connections in the heart–brain axis is considered, with the mechanisms by which emotional responses promote arrhythmias illustrated by inherited cardiac conditions. Novel therapeutic targets for intervention in the autonomic nervous system are considered.

Funder

UCL

UCLH Biomedicine NIHR

British Heart Foundation

Publisher

Oxford University Press (OUP)

Subject

General Medicine

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