Phase I study of gene-mediated cytotoxic immunotherapy with AdV-tk as adjuvant to surgery and radiation for pediatric malignant glioma and recurrent ependymoma

Author:

Kieran Mark W1,Goumnerova Liliana12,Manley Peter1,Chi Susan N1,Marcus Karen J13,Manzanera Andrea G45,Polanco Maria Lucia Silva45,Guzik Brian W45,Aguilar-Cordova Estuardo45,Diaz-Montero C Marcela6,DiPatri Arthur J7,Tomita Tadanori7,Lulla Rishi7,Greenspan Lianne1,Aguilar Laura K45,Goldman Stewart7

Affiliation:

1. Department of Pediatric Oncology, Dana-Farber Cancer Institute and Division of Pediatric Hematology/Oncology, Boston Children’s Hospital

2. Department of Neurosurgery, Boston Children’s Hospital

3. Department of Radiation Therapy, Dana-Farber Cancer Institute

4. Harvard Medical School, Boston, Massachusetts

5. Advantagene, Inc, Auburndale, Massachusetts

6. Department of Immunology, Cleveland Clinic, Cleveland, Ohio

7. Division of Hematology/Oncology, Ann & Robert H. Lurie Children’s Hospital of Chicago and Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois

Funder

Matthew Larson Foundation

Joe Andruzzi Foundation

CJ Buckley Brain Cancer Research Fund

Zach Carson Fund

Ellie Kavalieros DIPG Fund

Advantagene, Inc

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Neurology (clinical),Oncology

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