SNO-EANO-EURACAN consensus on management of pineal parenchymal tumors

Author:

Liu Anthony P Y12ORCID,Li Bryan K34,Vasiljevic Alexandre56,Dewan Michael C7,Tamrazi Benita8,Ertl-Wagner Birgit91011ORCID,Hansford Jordan R12,Pfaff Elke131415,Mynarek Martin1617ORCID,Ng Ho-Keung18,Tsang Derek S19,Gottardo Nicholas G20,Gajjar Amar21,Bouffet Eric2ORCID,Dufour Christelle2223ORCID,Pizer Barry24,Schiff David25ORCID,Jenkinson Michael D2627,Lombardi Giuseppe28ORCID,Wen Patrick Y29,van den Bent Martin J30ORCID,Huang Annie233132

Affiliation:

1. Department of Paediatrics and Adolescent Medicine, School of Clinical Medicine, The University of Hong Kong , Hong Kong , China

2. Division of Haematology/Oncology, The Hospital for Sick Children , Toronto, Ontario , Canada

3. Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto , Toronto, Ontario , Canada

4. Department of Pediatrics, Icahn School of Medicine at Mount Sinai , New York, New York , USA

5. Service D’Anatomie Et Cytologie Pathologiques, CHU de Lyon , Lyon , France

6. Faculté de Médecine Lyon Est, Université Claude Bernard , Lyon , France

7. Division of Pediatric Neurological Surgery, Vanderbilt University Medical Center , Tennessee , USA

8. Department of Radiology, Children’s Hospital Los Angeles , Los Angeles, California , USA

9. Division of Neuroradiology, Department of Diagnostic & Interventional Neuroradiology, The Hospital for Sick Children , Toronto, Ontario , Canada

10. Neurosciences and Mental Health Program, Research Institute, The Hospital for Sick Children , Toronto, Ontario , Canada

11. Department of Medical Imaging, University of Toronto , Toronto, Ontario , Canada

12. Michael Rice Centre for Hematology and Oncology, Women’s and Children’s Hospital; South Australia Health and Medical Research Institute; South Australia Immunogenomics Cancer Institute, University of Adelaide , Adelaide, South Australia , Australia

13. Department of Pediatric Oncology, Hematology and Immunology, Heidelberg University Hospital , Heidelberg , Germany

14. Pediatric Glioma Research Group (B360), German Cancer Research Center (DKFZ) , Heidelberg , Germany

15. Division of Pediatric Glioma Research, Hopp Children’s Cancer Center Heidelberg (KiTZ) , Heidelberg , Germany

16. Mildred Scheel Cancer Career Center HaTriCS4, University Medical Center Hamburg-Eppendorf , Hamburg , Germany

17. Department for Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf , Hamburg , Germany

18. Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Shatin, New Territories , Hong Kong , China

19. Radiation Medicine Program, Princess Margaret Cancer Centre , Toronto, Ontario , Canada

20. Department of Pediatric & Adolescent Oncology and Haematology, Perth Children’s Hospital and Brain Tumor Research Program, Telethon Kids Cancer Centre, Telethon Kids Institute, University of Western Australia , Perth , Western Australia , Australia

21. Department of Oncology, St. Jude Children’s Research Hospital , Memphis , Tennessee , USA

22. Department of Pediatric and Adolescent Oncology , Gustave Roussy , France

23. INSERM, Molecular Predictors and New Targets in Oncology, Paris-Saclay University , Villejuif , France

24. School of Life Sciences, University of Liverpool , Liverpool , UK

25. Division of Neuro-Oncology, Department of Neurology, University of Virginia, University of Virginia School of Medicine , Charlottesville , Virginia , USA

26. Department of Neurosurgery, The Walton Centre NHS Foundation Trust , Liverpool , UK

27. Institute of Systems, Molecular and Integrative Biology, University of Liverpool , Liverpool , UK

28. Department of Medical Oncology, Oncology 1, Veneto Institute of Oncology IOV-IRCCS , Padova , Italy

29. Center for Neuro-Oncology, Dana-Farber Cancer Institute , Boston , Massachusetts , USA

30. The Brain Tumor Center at Erasmus MC Cancer Institute, University Medical Center Rotterdam, Dr molewaterplein 40 , Rotterdam , The Netherlands

31. Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Children , Toronto , Ontario , Canada

32. Department of Medical Biophysics, Faculty of Medicine, University of Toronto , Toronto, Ontario , Canada

Abstract

Abstract Pineal parenchymal tumors are rare neoplasms for which evidence-based treatment recommendations are lacking. These tumors vary in biology, clinical characteristics, and prognosis, requiring treatment that ranges from surgical resection alone to intensive multimodal antineoplastic therapy. Recently, international collaborative studies have shed light on the genomic landscape of these tumors, leading to refinement in molecular-based disease classification in the 5th edition of the World Health Organization (WHO) classification of tumors of the central nervous system. In this review, we summarize the literature on diagnostic and therapeutic approaches, and suggest pragmatic recommendations for the clinical management of patients presenting with intrinsic pineal region masses including parenchymal tumors (pineocytoma, pineal parenchymal tumor of intermediate differentiation, and pineoblastoma), pineal cyst, and papillary tumors of the pineal region.

Publisher

Oxford University Press (OUP)

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3