Affiliation:
1. College of Pharmacy, Shandong University of Traditional Chinese Medicine , Jinan, Shandong Province , PR China
2. The Third Hospital of Jinan , Jinan, Shandong Province , PR China
3. Jinan Municipal Hospital of Traditional Chinese Medicine , Jinan, Shandong Province , PR China
4. Shandong Institute for Food and Drug Control , Jinan, Shandong Province , PR China
Abstract
AbstractObjectivesSolanum lyratum Thunb (SLT) is a perennial plant of the Solanaceae family, and is extensively used in the clinical practice of traditional Chinese medicine. Malaria, oedema, gonorrhoea, cancer, wind and fever, jaundiced hepatitis, cholecystitis and rheumatoid arthritis are among the diseases that it is used to treat. To offer a foundation for further development and usage of SLT, the pieces of literature about the chemical composition and pharmacological action of SLT were reviewed and analysed.Key findingsThe chemical constituents of SLT mainly included steroids, alkaloids, flavonoids, terpenoids, anthraquinones, phenylpropanoids and others. Pharmacological action mainly contains anti-tumour, antibacterial, anti-inflammatory, anti-oxidation and other pharmacological actions, among them, the anti-tumour effect is particularly outstanding.SummaryAt present, studies on the pharmacological effects of SLT mainly focus on alkaloids and steroidal saponins. In the follow-up studies, studies on the pharmacological activities of other chemical components in SLT, such as flavonoids and terpenoids, should be strengthened. It has the potential to pave the way for more research and development of novel SLT medicines.
Funder
Shandong Province Key Research and Development
Shandong postgraduate education quality curriculum
Shandong University of Traditional Chinese Medicine
Publisher
Oxford University Press (OUP)
Subject
Pharmaceutical Science,Pharmacology
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