Artificial Intelligence and Infectious Disease Imaging

Author:

Chu Winston T12ORCID,Reza Syed M S1,Anibal James T3,Landa Adam3,Crozier Ian4,Bağci Ulaş5,Wood Bradford J36,Solomon Jeffrey4

Affiliation:

1. Center for Infectious Disease Imaging, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health , Bethesda, Maryland , USA

2. Integrated Research Facility at Fort Detrick, Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health , Frederick, Maryland , USA

3. Center for Interventional Oncology, Clinical Center, National Institutes of Health , Bethesda, Maryland , USA

4. Clinical Monitoring Research Program Directorate, Frederick National Laboratory for Cancer Research sponsored by the National Cancer Institute , Frederick, Maryland , USA

5. Department of Radiology, Feinberg School of Medicine, Northwestern University , Chicago, Illinois , USA

6. Center for Interventional Oncology, National Cancer Institute, National Institutes of Health , Bethesda, Maryland , USA

Abstract

Abstract The mass production of the graphics processing unit and the coronavirus disease 2019 (COVID-19) pandemic have provided the means and the motivation, respectively, for rapid developments in artificial intelligence (AI) and medical imaging techniques. This has led to new opportunities to improve patient care but also new challenges that must be overcome before these techniques are put into practice. In particular, early AI models reported high performances but failed to perform as well on new data. However, these mistakes motivated further innovation focused on developing models that were not only accurate but also stable and generalizable to new data. The recent developments in AI in response to the COVID-19 pandemic will reap future dividends by facilitating, expediting, and informing other medical AI applications and educating the broad academic audience on the topic. Furthermore, AI research on imaging animal models of infectious diseases offers a unique problem space that can fill in evidence gaps that exist in clinical infectious disease research. Here, we aim to provide a focused assessment of the AI techniques leveraged in the infectious disease imaging research space, highlight the unique challenges, and discuss burgeoning solutions.

Funder

National Cancer Institute

National Institutes of Health

Clinical Monitoring Research Program Directorate

Frederick National Laboratory for Cancer Research

Clinical Center Radiology and Imaging Sciences Center for Infectious Disease Imaging

National Institute of Allergy and Infectious Diseases

Laulima Government Solutions

Tunnell Government Services

NIH Center for Interventional Oncology

NIH Intramural Research Program

NIH Clinical Center

National Institute of Biomedical Imaging and Bioengineering

NIH Intramural Targeted Anti-COVID-19

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Immunology and Allergy

Reference145 articles.

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