Distribution of Human Immunodeficiency Virus (HIV) Ribonucleic Acid in Cerebrospinal Fluid and Blood Is Linked to CD4/CD8 Ratio During Acute HIV

Author:

Chan Phillip1ORCID,Patel Payal2,Hellmuth Joanna3,Colby Donn J1,Kroon Eugène1,Sacdalan Carlo1,Pinyakorn Suteeraporn45,Jagodzinski Linda4,Krebs Shelly45,Ananworanich Jintanat145,Valcour Victor3,Spudich Serena26,

Affiliation:

1. SEARCH Thailand, Thai Red Cross AIDS Research Centre, Bangkok

2. Department of Neurology, Yale University School of Medicine, New Haven, Connecticut

3. Memory and Aging Center, Department of Neurology, University of California San Francisco

4. U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland

5. Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland

6. Center for Neuroepidemiology and Clinical Neurological Research, Yale University, New Haven, Connecticut

Funder

NIH

Henry M. Jackson Foundation

U.S. Department of Defense

National Institutes of Mental Health

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Immunology and Allergy

Reference40 articles.

1. Factors associated with neurocognitive test performance at baseline: a substudy of the INSIGHT Strategic Timing of AntiRetroviral Treatment (START) trial;Wright;HIV Med,2015

2. The neurological features of early and ‘latent’ human immunodeficiency virus infection;Brew;Aust N Z J Med,1989

3. Central nervous system viral invasion and inflammation during acute HIV infection;Valcour;J Infect Dis,2012

4. Neurologic signs and symptoms frequently manifest in acute HIV infection;Hellmuth;Neurology,2016

5. Central nervous system immune activation characterizes primary human immunodeficiency virus 1 infection even in participants with minimal cerebrospinal fluid viral burden;Spudich;J Infect Dis,2011

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