Association Study of Genes Controlling IL-12-dependent IFN-γ Immunity: STAT4 Alleles Increase Risk of Pulmonary Tuberculosis in Morocco

Author:

Sabri Ayoub12,Grant Audrey V.34,Cosker Kristel34,El Azbaoui Safa12,Abid Ahmed5,Abderrahmani Rhorfi Ismail5,Souhi Hicham5,Janah Hicham5,Alaoui-Tahiri Kebir5,Gharbaoui Yasser5,Benkirane Majid6,Orlova Marianna7,Boland Anne8,Deswarte Caroline34,Migaud Melanie34,Bustamante Jacinta349,Schurr Erwin7,Boisson-Dupuis Stephanie3410,Casanova Jean-Laurent341011,Abel Laurent3410,El Baghdadi Jamila1

Affiliation:

1. Genetics Unit, Military Hospital Mohamed V, Hay Riad, Rabat, Morocco

2. Faculty of Science-Kenitra, Ibn Tofail University, Kenitra, Morocco

3. Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale U1163, Paris, France

4. Paris Descartes University, Sorbonne Paris Cité, Imagine Institute, Paris, France

5. Department of Pneumology, Military Hospital Mohamed V, Hay Riad, Rabat, Morocco

6. Blood Transfusion Center, Military Hospital Mohamed V, Hay Riad, Rabat, Morocco

7. McGill International TB Centre, The Research Institute of the McGill University Health Centre, Montreal, Canada

8. CEA, Institut de Génomique, Centre National de Génotypage, Evry, France

9. Center for the Study of Primary Immunodeficiencies, AP-HP, Necker hospital, Paris France

10. St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, New York

11. Pediatric Hematology-Immunology Unit, AP-HP, Necker Hospital, Paris, France

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Immunology and Allergy

Reference42 articles.

1. Global tuberculosis control 2011;World Health Organization (WHO)

2. Tuberculosis;Zumla;N Engl J Med,2013

3. Tuberculosis in children and adults: two distinct genetic diseases;Alcaïs;J Exp Med,2005

4. Genetic dissection of immunity to mycobacteria: the human model;Casanova;Annu Rev Immunol,2002

5. The immunological life cycle of tuberculosis;Ernst;Nat Rev Immunol,2012

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