Prevalence of rosacea in transgender and gender-diverse populations: a retrospective cohort study

Author:

Sanz Jessika123ORCID,Gao Julia L4,King Dana S1,Modest Anna M56ORCID,Dommasch Erica D126

Affiliation:

1. The Fenway Institute, Fenway Health , Boston, MA , USA

2. Department of Dermatology, Beth Israel Deaconess Medical Center, Boston, MA, USA

3. New York Institute College of Osteopathic Medicine , Jonesboro, AR , USA

4. George Washington University School of Medicine & Health Sciences , Washington, DC , USA

5. Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Boston, MA, USA and

6. Harvard Medical School , Boston, MA , USA

Abstract

Hormones have been shown to affect the pathophysiology of rosacea, however, the prevalence of rosacea in transgender and gender diverse (TGD) patients on gender affirming hormone therapy (GAHT) has never been studied. Our retrospective cohort study showed a significantly decreased prevalence TGD patients on feminizing GAHT compared to cisgender men, women, and TGD not on GAHT. Our results suggest that estrogen and/or anti-androgenetic agents may play a protective role in the development or course of rosacea.

Funder

Beth Israel Deaconess Medical Center

Publisher

Oxford University Press (OUP)

Subject

Dermatology

Reference6 articles.

1. Effect of oral inhibitors of ovulation in treatment of rosacea and dermatitis perioralis in women;Spirov;Australas J Dermatol,1971

2. Oral spironolactone therapy in male patients with rosacea;Aizawa;J Dermatol,1992

3. Spironolactone may reduce the risk of incident rosacea;Spoendlin;J Invest Dermatol,2013

4. Experiences in dermatology with various contraceptives containing gestagen;Vankos;Gyogyszereink,1972

5. Prescribing for transgender patients;Tomlins;Aust Prescr,2019

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