Policy Statement: Antibiotic Stewardship in Pediatrics
Author:
Gerber Jeffrey S12, Jackson Mary Anne3, Tamma Pranita D4ORCID, Zaoutis Theoklis E12, Maldonado Yvonne A, O’Leary Sean T, Banerjee Ritu, Barnett Elizabeth D, Campbell James D, Caserta Mary T, Gerber Jeffrey S, Kourtis Athena P, Lynfield Ruth, Munoz Flor M, Nolt Dawn, Nyquist Ann-Christine, O’Leary Sean T, Steinbach William J, Zangwill Ken, Zaoutis Theoklis E, Kimberlin David W, Sawyer Mark H, Bernstein Henry H, Meissner H Cody, Cohn Amanda C, Farizo Karen M, Fischer Marc, Halasa Natasha B, Le Saux Nicole, Lopez Eduardo, Moore Scot B, Silverman Neil S, Steinberg Judith, Starke Jeffrey R, Stevermer James J, Tomashek Kay M, Frantz Jennifer M, Newland Jason, Hamdy Rana, Abuali Mayssa, Adams Daniel, Banerjee Ritu, Bula-Rudas Fernando, Dharmapalan Dhanya, Dulek Daniel, Flannery Dustin, Freij Bishara, Gainey Andrew, Gerber Jeffrey, Glaser Carol, Handy Lori, Hanisch Benjamin, Healy Sara, Hersh Adam, Hyun David, Johnson Candace, Katz Sophie, Kronman Matthew, Manaloor John, Maples Holly, Morris Lee, Onankpa Ben, Oram Ronda, Palazzi Debra, Schwenk Hayden, Shapiro Craig, Singh Prachi, Spicer Kevin, Tamma Pranita, TeKippe Michael, Thorell Emily, Tribble Alison, Willis Zachary, Woods Jon, Zembles Tracy, Phillips Terri Christene,
Affiliation:
1. Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA 2. Division of Infectious Diseases, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA 3. Department of Pediatrics, Section of Infectious Disease, Children’s Mercy Hospital, UMKC School of Medicine, Kansas City, Missouri, USA 4. Department of Pediatrics, Division of Pediatric Infectious Diseases, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Abstract
Abstract
Antibiotic overuse contributes to antibiotic resistance, which is a threat to public health. Antibiotic stewardship is a practice dedicated to prescribing antibiotics only when necessary and, when antibiotics are considered necessary, promoting the use of the appropriate agent(s), dose, duration, and route of therapy to optimize clinical outcomes while minimizing the unintended consequences of antibiotic use. Because there are differences in common infectious conditions, drug-specific considerations, and the evidence surrounding treatment recommendations (eg, first-line therapy and duration of therapy) between children and adults, this statement provides specific guidance for the pediatric population. This policy statement discusses the rationale for inpatient and outpatient antibiotic stewardship programs (ASPs); essential personnel, infrastructure, and activities required; approaches to evaluating their effectiveness; and gaps in knowledge that require further investigation. Key guidance for both inpatient and outpatient ASPs are provided.
Publisher
Oxford University Press (OUP)
Subject
Infectious Diseases,General Medicine,Pediatrics, Perinatology, and Child Health
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