Surface demineralized freeze-dried bone allograft followed by reimplantation in a failed mandibular dental implant

Author:

Zhang Jing12,Wang Jie12,You Jiayi12,Qin Xuan12,Chen Huimin3,Hu Xiantong456,Zhao Yantao456,Xia Yang12ORCID

Affiliation:

1. Jiangsu Key Laboratory of Oral Diseases, Nanjing Medical University , Nanjing, Jiangsu 210029, PR China

2. Jiangsu Province Engineering Research Center of Stomatological Translational Medicine, Nanjing Medical University , Nanjing, Jiangsu 210029, PR China

3. Department of Restorative Dental Sciences, Faculty of Dentistry, The University of Hong Kong , Hong Kong SAR, PR China

4. Senior Department of Orthopedics, The Fourth Medical Center of PLA General Hospital , Beijing, 100048, PR China

5. Beijing Engineering Research Center of Orthopedics Implants , Beijing 100048, PR China

6. State Key Laboratory of Military Stomatology , Xi'an 710032, PR China

Abstract

Abstract The removal of a failed implant with high torque causes significant damage to the surrounding tissue, compromising bone regeneration and subsequent osseointegration in the defect area. Here, we report a case of carrier screw fracture followed by immediate implant removal, bone grafting and delayed reimplantation. A dental implant with a fractured central carrier screw was removed using the bur-forceps technique. The resulting three-wall bone defect was filled with granular surface demineralized freeze-dried bone allograft (SD-FDBA). Cone-beam computerized tomography was performed at 1 week, 6 months and 15 months postoperatively and standardized for quantitative evaluation. The alveolar bone width and height at 15 months post-surgery were about 91% of the original values, with a slightly lower bone density, calculated using the gray value ratio. The graft site was reopened and was found to be completely healed with dense and vascularized bone along with some residual bone graft. Reimplantation followed by restoration was performed 8 months later. The quality of regenerated bone following SD-FDBA grafting was adequate for osseointegration and long-term implant success. The excellent osteogenic properties of SD-FDBA are attributed to its human origin, cortical bone-like structure, partly demineralized surfaces and bone morphogenetic protein-2-containing nature. Further investigation with more cases and longer follow-up was required to confirm the final clinical effect.

Funder

Natural Science Foundation of Jiangsu Province

Beijing Science Nova Program

Haidian Frontier Project of Beijing Natural Science Foundation

Publisher

Oxford University Press (OUP)

Subject

Biomaterials

Reference53 articles.

1. Dental implant restoration for dentition defects improves clinical efficacy, masticatory function and patient comfort;Zhong;Am J Transl Res,2022

2. Final-impression techniques and materials for making complete and removable partial dentures;Jayaraman;Cochrane Database Syst Rev,2018

3. Implant placement in the esthetic area: criteria for positioning single and multiple implants;Testori;Periodontol 2000,2018

4. Efficacy of a mineralized collagen bone-grafting material for peri-implant bone defect reconstruction in mini pigs;Wang;Regen Biomater,2019

5. Bone grafts and substitutes in dentistry: a review of current trends and developments;Zhao;Molecules,2021

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