Identification of Bacterial and Viral Codetections With Mycoplasma pneumoniae Using the TaqMan Array Card in Patients Hospitalized With Community-Acquired Pneumonia

Author:

Diaz Maureen H.1,Cross Kristen E.1,Benitez Alvaro J.1,Hicks Lauri A.1,Kutty Preeta1,Bramley Anna M.2,Chappell James D.3,Hymas Weston4,Patel Anami56,Qi Chao7,Williams Derek J.38,Arnold Sandra R.56,Ampofo Krow4,Self Wesley H.3,Grijalva Carlos G.3,Anderson Evan J.9,McCullers Jonathan A.5610,Pavia Andrew T.4,Wunderink Richard G.7,Edwards Kathryn M.38,Jain Seema2,Winchell Jonas M.1

Affiliation:

1. Division of Bacterial Diseases

2. Influenza Division, Centers for Disease Control, and Prevention, Atlanta, Georgia

3. Vanderbilt University School of Medicine, Nashville, Tennessee

4. University of Utah Health Sciences Center, Salt Lake City

5. Le Bonheur Children's Hospital, Memphis, Tennessee

6. University of Tennessee Health Science Center, Memphis

7. Northwestern University Feinberg School of Medicine, Chicago, Illinois

8. Vanderbilt Vaccine Research Program, Nashville, Tennessee

9. Emory University School of Medicine, Atlanta, Georgia

10. St. Jude Children's Research Hospital, Memphis, Tennessee

Abstract

Abstract Mycoplasma pneumoniae was detected in a number of patients with community-acquired pneumonia in a recent prospective study. To assess whether other pathogens were also detected in these patients, TaqMan Array Cards were used to test 216 M pneumoniae-positive respiratory specimens for 25 additional viral and bacterial respiratory pathogens. It is interesting to note that 1 or more codetections, predominantly bacterial, were identified in approximately 60% of specimens, with codetections being more common in children.

Funder

Influenza Division in the National Center for Immunization and Respiratory Diseases

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

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