Robust evidence for five new Graves' disease risk loci from a staged genome-wide association analysis

Author:

Zhao Shuang-Xia12,Xue Li-Qiong1,Liu Wei1,Gu Zhao-Hui13,Pan Chun-Ming1,Yang Shao-Ying1,Zhan Ming1,Wang Hai-Ning1,Liang Jun4,Gao Guan-Qi5,Zhang Xiao-Mei6,Yuan Guo-Yue7,Li Chang-Gui8,Du Wen-Hua5,Liu Bing-Li1,Liu Li-Bin9,Chen Gang10,Su Qing11,Peng Yong-De12,Zhao Jia-Jun13,Ning Guang12,Huang Wei14,Liang Liming15,Qi Lu1617,Chen Sai-Juan1,Chen Zhu1,Chen Jia-Lun2,Song Huai-Dong12,

Affiliation:

1. State Key Laboratory of Medical Genomics and

2. Department of Endocrinology, Shanghai Institute of Endocrinology and Metabolism, Ruijin Hospital Affiliated to Shanghai Jiaotong University (SJTU) School of Medicine, Shanghai 200025, China,

3. Shanghai Center for Systems Biomedicine, SJTU, Shanghai 200240, China,

4. Department of Endocrinology, The Central Hospital of Xuzhou Affiliated to Xuzhou Medical College, Xuzhou, Jiangsu Province 221109, China,

5. Department of Endocrinology, Linyi People's Hospital, Linyi, Shandong Province 276003, China,

6. Department of Endocrinology, The First Hospital Affiliated to Bengbu Medical College, Bengbu, Anhui Province 233004, China,

7. Department of Endocrinology, The Hospital Affiliated to Jiangsu University, Zhenjiang, Jiangsu Province 213001, China,

8. Department of Endocrinology and Gout Laboratory, Medical School Hospital of Qingdao University, Qingdao, Shandong Province 266003, China,

9. Department of Endocrinology, Xiehe Hospital Affiliated to Fujian Medical University, Fuzhou, China,

10. Department of Endocrinology, Fujian Province Hospital, Fuzhou, Fujian Province 350001, China,

11. Department of Endocrinology, Xin-Hua Hospital Affiliated to SJTU School of Medicine, Shanghai 200092, China,

12. Department of Endocrinology, The First People's Hospital Affiliated to SJTU School of Medicine, Shanghai 200080, China,

13. Department of Endocrinology, Shandong Province Hospital Affiliated to Shandong University, Jinan, Shandong Province 250021, China,

14. Department of Genetics, Shanghai-MOST Key Laboratory of Health and Disease Genomics, Chinese National Human Genome Center, Shanghai 201303, China,

15. Department of Epidemiology and Biostatistics and

16. Department of Nutrition, Harvard School of Public Health, Boston, MA 021216, USA and

17. Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 021216, USA

Publisher

Oxford University Press (OUP)

Subject

Genetics(clinical),Genetics,Molecular Biology,General Medicine

Reference57 articles.

1. Serum TSH and total T4 in the United States population and their association with participant characteristics: National Health and Nutrition Examination Survey (NHANES 1999–2002);Aoki;Thyroid,2007

2. The effect of salt iodization for 10 years on the prevalences of endemic goiter and hyperthyroidism;Chen;Chin. J. Endocrinol. Metab.,2000

3. Evidence for a major role of heredity in Graves' disease: a population-based study of two Danish twin cohorts;Brix;J. Clin. Endocrinol. Metab.,2001

4. Genetic susceptibility to autoimmune thyroid disease: past, present, and future;Tomer;Thyroid,2010

5. Association of the CTLA4 gene with Graves' disease in the Chinese Han population;Zhao;PloS One,2010

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