Programmed cell death protein 1 and tyrosine kinase inhibition plus transcatheter arterial chemoembolization of advanced hepatocellular carcinoma

Author:

Peng Wei12,Zhang Xiaoyun1,Li Chuan1ORCID,Zhu Xinrui1,Li Qiu3,Chen Weixia4,Lu Wusheng1,Liu Chang1,Zhou Yongjie5,Shi Yujun5,Wen Tianfu1ORCID,Sun Xin2

Affiliation:

1. Department of Liver Surgery, West China Hospital, Sichuan University , Chengdu , China

2. Chinese Evidence-based Medicine Centre, West China Hospital, Sichuan University , Chengdu , China

3. Department of Medical Oncology, Cancer Centre, West China Hospital, Sichuan University , Chengdu , China

4. Department of Radiology, West China Hospital, Sichuan University , Chengdu , China

5. Laboratory of Pathology, Key Laboratory of Transplant Engineering and Immunology, NHC, West China Hospital, Sichuan University , Chengdu , China

Abstract

The IDEAL framework allowed safe introduction of salvage liver resection after LEN-TAP strategy in an evidence-based manner without exposing the initial patients to unacceptable risk. The findings showed that LEN-TAP conversion strategy is feasible with manageable AEs for uHCC, and salvage liver resection is safe and beneficial.

Publisher

Oxford University Press (OUP)

Subject

Surgery

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