1. Department of Medical Research, Taipei Veterans General Hospital , Taipei , Taiwan
2. Faculty of Medicine, National Yang Ming Chiao Tung University , Taipei , Taiwan
3. Institute of Pharmacology, National Yang Ming Chiao Tung University , Taipei , Taiwan
4. Division of Gastroenterology and Hepatology, Min-Sheng General Hospital , Taoyuan , Taiwan
5. Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital , Taipei , Taiwan