Comparison of idiopathic and drug-induced epidermal necrolysis in children

Author:

Welfringer-Morin Anne12,Bataille Pauline1,Drummond David3,Bellon Nathalia12,Ingen-Housz-Oro Saskia24ORCID,Bonigen Julie5ORCID,Schmartz Sophie3,Giraud-Kerleroux Laura4,Moulin Florence5,De Saint Blanquat Laure5,Bremond-Gignac Dominique6,Hadj-Rabia Smail1,Bodemer Christine12

Affiliation:

1. Department of Paediatric Dermatology

2. Reference Center for Toxic Bullous Dermatoses and Severe Drug Reactions (TOXIBUL) , Paris , France

3. Department of Paediatric Pulmonology and Allergology

4. Department of Dermatology, AP-HP, Henri Mondor Hospital, University Paris-Est Créteil EpidermE , Créteil , France

5. Paediatric Intensive Care Unit, Necker-Enfants Malades Hospital, University Paris Cité , AP-HP , France

6. Department of Ophthalmology, Necker-Enfants Malades Hospital, University Paris Cité , AP-HP, Paris , France

Abstract

In this monocentric retrospective study in a French paediatric reference centre, children with idiopathic epidermal necrolysis (EN) had more severe disease than those with drug-induced EN during the acute stage. In our study, no EN was attributed to infection.

Publisher

Oxford University Press (OUP)

Subject

Dermatology

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