Ligament Advanced Reinforcement System (LARS) synthetic graft for PCL reconstruction: systematic review and meta-analysis

Author:

Migliorini Filippo123,Pintore Andrea45,Vecchio Gianluca45,Oliva Francesco45,Hildebrand Frank123,Maffulli Nicola4567891011

Affiliation:

1. Department of Orthopaedics , , , 52064 Aachen, Germany

2. University Clinic Aachen , , , 52064 Aachen, Germany

3. RWTH Aachen University Clinic , , , 52064 Aachen, Germany

4. Department of Orthopaedics , Surgery and Dentistry, , Via S. Allende, 84081 Baronissi, Italy

5. University of Salerno , Surgery and Dentistry, , Via S. Allende, 84081 Baronissi, Italy

6. Department of Orthopedic and Trauma Surgery , , 076063 Potenza, Italy

7. Ospedale San Carlo , , 076063 Potenza, Italy

8. Queen Mary University of London , , 275 Bancroft Road, London E1 4DG, UK

9. Barts and the London School of Medicine and Dentistry, Centre for Sports and Exercise Medicine, Mile End Hospital , , 275 Bancroft Road, London E1 4DG, UK

10. School of Pharmacy and Bioengineering , , Thornburrow Drive, 01782 Stoke on Trent, UK

11. Keele University Faculty of Medicine , , Thornburrow Drive, 01782 Stoke on Trent, UK

Abstract

Abstract Introduction Several strategies are available for posterior cruciate ligament (PCL) reconstruction. Source of data Recently published literature in PubMed, Google Scholar and Embase databases. Areas of agreement The Ligament Advanced Reinforcement System (LARS) is a scaffold type artificial ligament, which has been widely used for ligament reconstruction of the knee. Areas of controversy Current evidence on the reliability and feasibility of LARS for primary isolated PCL reconstruction is limited. Growing points The primary outcome of interest of the present work was to investigate the outcomes of PCL reconstruction using the LARS. The secondary outcome of interest was to compare the LARS versus four-strand hamstring tendon (4SHT) autograft for PCL reconstruction. Areas timely for developing research LARS for primary isolated PCL reconstruction seems to be effective and safe, with results comparable to the 4SHT autograft.

Publisher

Oxford University Press (OUP)

Subject

General Medicine

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