Older Adults With Inflammatory Bowel Disease Are at Higher Risk of Developing Antibodies to Infliximab-Reference-Cited by-同舟云学术

Older Adults With Inflammatory Bowel Disease Are at Higher Risk of Developing Antibodies to Infliximab

Published:2024-01-03 Issue: Volume: Page:
ISSN:1078-0998
Container-title:Inflammatory Bowel Diseases
language:en
Short-container-title:

Author:

Faye Adam S¹,Lee Kate E²^ORCID,Hudesman David¹,Dervieux Thierry³

Affiliation:

1. Division of Gastroenterology, NYU Grossman School of Medicine , New York, NY , USA

2. Department of Medicine, Duke University Medical Center , Durham, NC , USA

3. Prometheus Laboratories , San Diego, CA , USA

Abstract

Lay Summary Although older age is thought to confer immunosenescence, we found that older adults with inflammatory bowel disease are independently at higher risk to develop antibodies to infliximab. Additionally, older adults are less likely to receive escalated doses of infliximab.

Publisher

Oxford University Press (OUP)

Link

https://academic.oup.com/ibdjournal/advance-article-pdf/doi/10.1093/ibd/izad305/54973590/izad305.pdf

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