Investing in Late-Life Brain Capital

Author:

Dawson Walter D123,Smith Erin234,Booi Laura235,Mosse Maia4,Lavretsky Helen6,Reynolds Charles F7,Cummings Jeffrey8,Brannelly Patrick9,Hynes William4,Lenze Eric J10,Manes Facundo1112,Ayadi Rym13,Frank Lori14,Chapman Sandra Bond15,Robertson Ian H2315,Rubenstein Lori16,Jraissati Jorge17,Ibáñez Agustin2318,Fillit Howard1920,Jeste Dilip V2122ORCID,Rao Anitha2324,Berk Michael2526ORCID,Storch Eric A27,Santuccione Chadha Antonella2829,Eyre Harris A2530

Affiliation:

1. Department of Neurology, School of Medicine, Oregon Health & Science University , Portland, Oregon , USA

2. Global Brain Health Institute at University of California, San Francisco (UCSF) , San Francisco, California , USA

3. Trinity College Dublin , Dublin , Ireland

4. Department of Medicine, Stanford Hospital , Stanford, California , USA

5. Centre for Dementia Research, School of Health, Leeds Beckett University , Leeds , UK

6. Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles (UCLA) , Los Angeles, California , USA

7. Department of Psychiatry, University of Pittsburgh , Pittsburgh, Pennsylvania , USA

8. Chambers-Grundy Center for Transformative Neuroscience, Department of Brain Health, School of Integrated Health Sciences, University of Nevada, Las Vegas , Las Vegas, Nevada , USA

9. Alzheimer’s Disease Data Initiative, Gates Ventures , Redwood City, California , USA

10. Department of Psychiatry, Washington University School of Medicine , St Louis, Missouri , USA

11. Institute of Cognitive and Translational Neuroscience (INCYT), INECO Foundation, Favaloro University , Buenos Aires , Argentina

12. National Scientific and Technical Research Council (CONICET) , Buenos Aires , Argentina

13. Euro-Mediterranean Economists Association , Barcelona , Spain

14. RAND Corporation , Arlington, Virginia , USA

15. Center for BrainHealth®, The University of Texas at Dallas , Dallas, Texas , USA

16. Australian Research Alliance for Children and Youth (ARACY) , Canberra, Australian Capital Territory , Australia

17. IESE Center for Public Leadership and Government, IESE Business School , Madrid , Spain

18. Latin American Brain Health Institute (BrainLat), Universidad Adolfo Ibáñez , Santiago , Chile

19. Alzheimer’s Drug Discovery Foundation (ADDF) , New York City, New York , USA

20. Departments of Geriatric Medicine, Palliative Care and Neuroscience, The Icahn School of Medicine at Mount Sinai , New York City, New York , USA

21. Departments of Psychiatry and Neurosciences, University of California San Diego , La Jolla, California , USA

22. IBM-UC San Diego Center for Artificial Intelligence for Healthy Living, University of California San Diego , La Jolla, California , USA

23. Neurocern , Chicago, Illinois , USA

24. Department of Neurology, University of Toledo College of Medicine and Life Sciences , Toledo, Ohio , USA

25. IMPACT, the Institute for Mental and Physical Health and Clinical Translation, Deakin University , Geelong, Victoria , Australia

26. Department of Psychiatry, University of Melbourne , Melbourne, Victoria , Australia

27. Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine , Houston, Texas , USA

28. Biogen , Cambridge, Massachusetts , USA

29. Women’s Brain Project , Zurich , Switzerland

30. Neuroscience-inspired Policy Initiative, Organisation for Economic Co-operation and Development (OECD) and the PRODEO Institute , Paris , France

Abstract

Abstract Within many societies and cultures around the world, older adults are too often undervalued and underappreciated. This exacerbates many key challenges that older adults may face. It also undermines the many positive aspects of late life that are of tremendous value at both an individual and societal level. We propose a new approach to elevate health and well-being in late life by optimizing late-life Brain Capital. This form of capital prioritizes brain skills and brain health in a brain economy, which the challenges and opportunities of the 21st-century demands. This approach incorporates investing in late-life Brain Capital, developing initiatives focused on building late-life Brain Capital.

Funder

CONICET

ANID/FONDECYT Regular

FONCYT-PICT

ANID/FONDAP

Takeda Foundation

Sistema General de Regalías

Universidad del Valle

Alzheimer’s Association GBHI ALZ

Multi-Partner Consortium to Expand Dementia Research in Latin America

National Institutes of Health

National Institute on Aging

Rainwater Charitable Foundation—Tau Consortium

Global Brain Health Institute

NHMRC Senior Principal Research Fellowship

Eunice Kennedy Shriver National Institute of Child Health and Human Development

Oregon Health Authority

Alzheimer's Association

National Institute of General Medical Sciences

National Institute of Neurological Disorders and Stroke

Publisher

Oxford University Press (OUP)

Subject

Life-span and Life-course Studies,Health Professions (miscellaneous),Health (social science)

Reference18 articles.

1. Should robots pay taxes? Tax policy in the age of automation;Abbott;Harvard Law and Policy Review,2018

2. Brain health: Key to health, productivity, and well-being;Avan;Alzheimer’s & Dementia,2021

3. A Novel BrainHealth Index Prototype Improved by Telehealth-Delivered Training During COVID-19;Chapman,2021

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