Candidate-based screening via gene modulation in human neurons and astrocytes implicates FERMT2 in Aβ and TAU proteostasis

Author:

Sullivan Sarah E1,Liao Meichen1,Smith Robert V1,White Charles2,Lagomarsino Valentina N1,Xu Jishu3,Taga Mariko2,Bennett David A4,De Jager Philip L32,Young-Pearse Tracy L1

Affiliation:

1. Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA

2. Center for Translational and Computational Neuroimmunology, Department of Neurology, Columbia University Medical Center, New York, NY, USA

3. Cell Circuits Program, Broad Institute, Cambridge, MA, USA

4. Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA

Funder

National Institute on Aging

BrightFocus Foundation

Publisher

Oxford University Press (OUP)

Subject

Genetics(clinical),Genetics,Molecular Biology,General Medicine

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